Patents (1436 Stem Cell Patents)

Method of isolating human neuroepithelial precursor cells from human fetal tissue

Patent Number: 7,517,521

Date of First Priority Issue: Wednesday March 21st, 2001
Date Issued: Tuesday April 14th, 2009
Assignee: University of Utah Research Foundation (Salt Lake City, UT)
Inventors: Mayer-Proschel; Margot (Pittsford, NY), Rao; Mahendra S. (Salt Lake City, UT), Tresco; Patrick A. (Sandy, UT), Messina; Darin J. (Salt Lake City, UT)

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This patent covers methods of using a type of fetal stem cell in experimental systems or in humans.  It seems to be a clever claiming strategy. 

Essentially the patent claims a method for transplanting an isolated population of human neuroepithelial precursor cells into an animal comprising: (a) isolating human neuroepithelial precursor cells from human fetal tissue by a method which comprises (i) culturing human fetal cells in medium containing fibroblast growth factor and chick embryo extract; and (ii) immunodepleting from the cultured human fetal cells any cells expressing A2B5, NG2 and eNCAM so that an isolated population of human neuroepithelial precursor cells remains; and (b) transplanting the isolated human neuroepithelial precursor cells into the central nervous system of an animal, wherein said animal is immunosuppressed or is a human.

View this patent on the USPTO website.

Added to StemCellPatents.com on Monday April 20th, 2009

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