This patent covers the expansion of endothelial cells by growing on collagen-1 coated plates in the combination of various growth factors such as FGF, VEGF, and IGF. Additionally, numerous culture conditions for endothelial expansion are disclosed.
The abstract of the patent discribes the use of endothelial cells for gene therapy, but not the claims. The disclosure also describes how endothelial cells that are expanded can be used as vectors for delivering genes to areas of the body to which they are specifically needed.
View this patent on the USPTO website.
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