Mammalian myeloid progenitor cell subsets
Patent Number: 6465247
Date of First Priority Issue: Tuesday June 29th, 1999
Date Issued: Tuesday October 15th, 2002
Assignee: The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA)
Inventors: Weissman, Irving L. (Redwood City, CA); Traver, David Jeffrey (West Roxbury, MA); Akashi, Koichi (Palo Alto, CA)
From Class: Type
Comments: No comments
This patent covers a type of stem cell that has differentiated and is committed to the myeloid lineage. This stem cell is useful for inducing a rapid production of myeloid cells such as granulocytes and monocytes, which are protective against bacteria.
The cells covered in the patent display the phenotype of c-kit positive, negative for IL-7 receptor (most likely since IL-7 is associated with the lymphoid progenitors), and negative for markers of differentiated cells such as B220 (B cells), CD4 (T cells), CD8 (T cells), CD3 (T cells), Gr-1 (neutrophils) and Mac-1 (monocyte/macrophage).
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
Social & Bookmarking:
Add Comment
You must be signed-in to add your comments.
Sign-in now or Join the StemCellPatents.com Community for free.