Human marrow stromal cell lines which sustain hematopoiesis
Patent Number: 6103522
Date of First Priority Issue: Wednesday July 20th, 1994
Date Issued: Tuesday August 15th, 2000
Assignee: Fred Hutchinson Cancer Research Center (Seattle, WA)
Inventors: Torok-Storb, Beverly (Seattle, WA); Roecklein, Bryan A. (Seattle, WA); Johnson, Gretchen (Issaquah, WA)
From Class: Type
Comments: No comments
Culture of early hematopoietic stem cells (human ones) was previously performed on murine stromal cells, and stromal cells of mouse that are transfected with certain genes. In this patent a human stromal cell line is provided (can be bought at ATCC), which is capable of sustaining expansion of early human hematopoietic stem cells. This cell line allows for growth and generation of human hematopoietic stem cells without having to worry about contamination from animal components.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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