Patents (1436 Stem Cell Patents)

Universal donor cells

Patent Number: 6100443

Date of First Priority Issue: Monday June 12th, 1989
Date Issued: Tuesday August 8th, 2000
Assignee: Oklahoma Medical Research Foundation (Oklahoma City, OK); Yale University (New Haven, CT)
Inventors: Sims, Peter J. (Mequon, WI); Bothwell, Alfred L. M. (Guilford, CT); Elliot, Eileen A. (New Haven, CT); Flavell, Richard A. (Killingworth, CT); Madri, Joseph (North Branford, CT); Rollins, Scott (Monroe, CT); Bell, Leonard (Woodbridge, CT); Squinto, Stephe

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This patent covers non-human cells and stem cells that are "de-immunogenized" so that they may be transplanted into humans without rejection. The patent "de-immunogenizes" the cells by inducing expression of human anticomplement proteins, as well as by suppressing the expression of immunogenic proteins such as those of the MHC type.

View this patent on the USPTO website.

Added to StemCellPatents.com on Monday October 16th, 2006

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