Universal donor cells
Patent Number: 5705732
Date of First Priority Issue: Monday June 12th, 1989
Date Issued: Tuesday January 6th, 1998
Assignee: Oklahoma Medical Research Foundation (Oklahoma City, OK); Yale University (New Haven, CT)
Inventors: Sims, Peter J. (Mequon, WI); Bothwell, Alfred L.M. (Guilford, CT); Elliot, Eileen A. (New Haven, CT); Flavell, Richard A. (Killingworth, CT); Madri, Joseph (North Branford, CT); Rollins, Scott (Monroe, CT); Bell, Leonard (Woodbridge, CT); Squinto, Stephen
This patent covers manipulated cells and stem cells that are not immunogeneic when inplanted into a recipient. Various means of reducing immunogenecity are disclosed such as expression of human complement inhibitors and deletion or suppression of MHC expression.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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