Mammalian neural crest stem cells
Patent Number: 5589376
Date of First Priority Issue: Monday July 27th, 1992
Date Issued: Saturday December 21st, 1996
Assignee: California Institute of Technology (Pasadena, CA)
Inventors: Anderson, David J. (Altadena, CA); Stemple, Derek L. (Pasadena, CA)
From Class: Type
Comments: No comments
This patent covers a type of neural stem cell that is derived from the neural crest and expresses a specific phenotypic profile that allows not only for isolation, but also in vitro and in vivo identification.
This stem cell type is capable of differentiating into neurons similar to those found in the peripheral nervious system, as well as microglia.
The cell has a phenotype of LNGFR+, nestin+ but GFAP negative.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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