The use of epithelial cells (such as fibroblasts) transfected with telomerase for acceleration of wound healing is covered by this patent. This invention is conceptually attractive, however the possible effects of telomerase transfection in terms of immortalization of cells showed be consided. Since wounds already express inflammatory mediators such as free radicals (which damage DNA), would not the addition of immortalized or semi-immortalized cells increase likelihood of neoplasia?
View this patent on the USPTO website.
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