Interview with Novocell CEO Alan Lewis
In this StemCellPatents.com interview, our special guest interviewer, Thomas Ichim, CEO of Medistem, speaks with Alan Lewis, CEO of Novocell, regarding the company's advances towards curing diabetes. This interview examines many aspects of Novocell which include: the history of Novocell and how the company was formed; their strategy for being a leading-edge researcher in using stem cells for curing diabetes; and their encapsulation technology. Huntington Beach, CA - A recent paper from Dr. Agadjanyan's group at the Institute of Molecular Medicine (Movsesyan et al. Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy. PLoS ONE 2008 May 7;3(5):e2124) reports the successful treatment of a mouse model of Alzheimer's using DNA vaccination against amyloid protein peptides. Previously clinical trials were conducted using vaccination towards amyloid protein. Efficacy was associated with antibody responses. Autoreactivity... [Read more] Münster, Germany - Understanding and manipulating the formation of new blood vessels, a process called angiogenesis, has been one of the highly sought-after goals of the biotechnology industry. One the one hand, inhibition of angiogenesis is desirable in cancer, since tumors need new blood vessels to stay alive. On the other hand, angiogenesis stimulation could be a beneficial treatment for diseases such as ischemic heart failure and other types of conditions associated with poor circulation. Critical limb ischemia is an advanced form of peripheral... [Read more] Naples, Italy - The administration of bone marrow stem cells into ischemic muscles for treatment of critical limb ischemia is currently being performed in clinical trials, with results demonstrating stimulation of angiogenesis and functional improvement. Given that a substantial amount of the angiogenic response seems to be dependent on endogenous stem cell mobilization, one interesting idea is to mobilize endogenous stem cells without adding exogenous ones. This is what scientists have reported in a recent... [Read more]
Immunology Instead of Stem Cells: Vaccine for Alzheimer's
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