Increase in hematopoietic progenitor cells in peripheral blood by transforming growth factor beta
Patent Number: 5426098
Date of First Priority Issue: Thursday September 2nd, 1993
Date Issued: Tuesday June 20th, 1995
Assignee: Celtrix Pharmaceuticals, Inc. (Santa Clara, CA)
Inventor: Carlino, Joseph A. (San Leandro, CA)
From Class: Expansion
Comments: No comments
This patent leverages the ability of TGF-beta to protect stem cells from cytotoxic agents by inhibiting proliferation of stem cells. Specifically, since chemotherapy kills proliferating cells, if the hematopoietic stem cells are first stopped from proliferating by administration of TGF-beta, then the hematopoietic system should be preserved, at least in part.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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