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A paper was published last week in which adult bone marrow mesenchymal stem cells were transfected with the IGF-1 gene and used to treat animals after cardiac infarction.  Animals treated with the genetically modified stem cells exhibited better recovery as compared to controls recieving sham transfected cells.  Most interestingly, the authors demonstrated that the protective effect was associated with mobilization of endogenous stem cells. 

2 patents of interest to our field were recently issued.  The first #7,439,332 teaches a new polypeptide that stimulates erythropoiesis.  Perhaps most interesting about this patent was how they discovered the compound.  The second #7,439,064 is another one of Jamie Thomson's masterpieces, this time disclosing a serum-free, feeder-free method of maintaining embryonic stem cells in culture without spontaneous differentation.  The broadness of the first claim will strike you.

 


Method for enhancing engraftment of cells using mesenchymal progenitor cells
 
 
Patent Number: 7,442,390

Stem cell transplantation in the form of cord blood, mobilized peripheral blood, or bone marrow, has saved many lives.  One of the limiting factors of this procedure is graft versus host disease (GVHD).  The other is poor...[Read More]

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  Potentiating Mesenchymal Stem Cells for Cardiac Regeneration

Sunday October 26th, 2008 @ 12:13:01 EST

Cincinnati, Ohio -

Mesenchymal stem cells are attractive for therapeutics development because they can theoretically be used as a "one size fits all".  Additionally, their ability to home to area of tissue injury, in part by [Read More]

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The Stem Cell Meeting 

Stem Cells World Congress

RMSC 2008 World Congress (2-4 December 2008)
The 3rd Annual Stem Cells World Congress (20-22 January 2009)
The Stem Cell Meeting (March 2009)

 


  RECENTLY ADDED PATENTS  
  Mammary stem cell marker (7,563,619)
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  Soft tissue repair and regeneration using postpartum-derived cells (7,560,276)
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  Compositions and methods for generating skin (7,560,275)
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  Method for reducing neuronal degeneration so as to ameliorate the effects of injury or disease (7,560,102)
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  Human cord blood derived unrestricted somatic stem cells (USSC) (7,560,280)
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  Human cord blood derived unrestricted somatic stem cells (USSC) (7,556,801)
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  Dedifferentiated, programmable stem cells of monocytic origin, and their production and use (7,553,663)
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  Stromal antigen-presenting cells and use thereof (7,553,661)
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  Directed in vitro differentiation of marrow stromal cells into neural cell progenitors (7,547,545)
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  Progenitor cells from wharton's jelly of human umbilical cord (7,547,546)
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  View all 1436 Stem Cell Patents on StemCellPatents.com  


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