
Hello ,
A paper was published last week in which adult bone marrow mesenchymal stem cells were transfected with the IGF-1 gene and used to treat animals after cardiac infarction. Animals treated with the genetically modified stem cells exhibited better recovery as compared to controls recieving sham transfected cells. Most interestingly, the authors demonstrated that the protective effect was associated with mobilization of endogenous stem cells.
2 patents of interest to our field were recently issued. The first #7,439,332 teaches a new polypeptide that stimulates erythropoiesis. Perhaps most interesting about this patent was how they discovered the compound. The second #7,439,064 is another one of Jamie Thomson's masterpieces, this time disclosing a serum-free, feeder-free method of maintaining embryonic stem cells in culture without spontaneous differentation. The broadness of the first claim will strike you.
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RMSC 2008 World Congress (2-4 December 2008)
The 3rd Annual Stem Cells World Congress (20-22 January 2009)
The Stem Cell Meeting (March 2009)
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