StemCellPatents.com Newsletter

Hello ,

Although the majority of studies looking at stem cell mediated immune modulation have been focused on mesenchymal stem cells, a recent paper describes suppression of the mouse model of MS through administration of hematopoietic stem cells, and demonstrated that therapeutic effect was associated with upregulation of indolamine 2,3 deoxygenase in the dendritic cells. 

Osiris continues to advance its patent portfolio, last week being issued patent # 7,491,388, which covers the use of fibroblasts for prevention of graft versus host disease. 

A stunning example of creativity was patent #7,491,534 which teaches how to generate T cells from fibroblasts !! and as if that was not enough, teaches how to select the T cells for specific T cell receptors so that they may be used in immunotherapy.  Very Very Interesting !

Uses of fibroblasts or supernatants from fibroblasts for the suppression of immune responses in transplantation     Patent Number: 7,491,388 Assignee | Inventor We know that mesenchymal stem cells are immune modulatory through a variety of means such as secretion of HLA-G, expression of indolamine 2,3 deoxygenase, and production of immune suppressive cytokines.  What is relatively understudied is the immune...[Read More] Ask a question OR leave your comments.

Stem Cell Inhibition of Multiple Sclerosis by IDO Induction Sunday February 22nd, 2009 @ 23:52:52 EST [Watch the Video]  Lodz, Poland - One of the very interesting things is trying to figure out how stem cells mediate their therapeutic effects in conditions such as multiple sclerosis.  In general there are three main ways: 1) Differentiation into...[Read More] Ask a question OR leave your comments. Read more StemCellPatents.com News

Media Partnerships (NEW)

RECENTLY ADDED PATENTS     Mammary stem cell marker (7,563,619) Assignee | Inventor | Ask a question OR leave your comments     Soft tissue repair and regeneration using postpartum-derived cells (7,560,276) Assignee | Inventor | Ask a question OR leave your comments     Compositions and methods for generating skin (7,560,275) Assignee | Inventor | Ask a question OR leave your comments     Method for reducing neuronal degeneration so as to ameliorate the effects of injury or disease (7,560,102) Assignee | Inventor | Ask a question OR leave your comments     Human cord blood derived unrestricted somatic stem cells (USSC) (7,560,280) Assignee | Inventor | Ask a question OR leave your comments     Human cord blood derived unrestricted somatic stem cells (USSC) (7,556,801) Assignee | Inventor | Ask a question OR leave your comments     Dedifferentiated, programmable stem cells of monocytic origin, and their production and use (7,553,663) Assignee | Inventor | Ask a question OR leave your comments     Stromal antigen-presenting cells and use thereof (7,553,661) Assignee | Inventor | Ask a question OR leave your comments     Directed in vitro differentiation of marrow stromal cells into neural cell progenitors (7,547,545) Assignee | Inventor | Ask a question OR leave your comments     Progenitor cells from wharton's jelly of human umbilical cord (7,547,546) Assignee | Inventor | Ask a question OR leave your comments     View all 1436 Stem Cell Patents on StemCellPatents.com

LATEST NEWS     Leptin Blocks T Regulatory Cell Expansion August 23rd, 2009     Mechanism of Multiple Sclerosis Stem Cell Therapy July 24th, 2009 : 2 Comments     Lithium for Treatment of Multiple Sclerosis July 15th, 2009     Treatment of Degenerative Disc Disease by Bone Marrow Stem Cells July 9th, 2009 : 2 Comments     Apoptotic Cells Secrete Angiogenic Factors June 27th, 2009     Read more news on StemCellPatents.com

LATEST JOBS POSTS     View the StemCellPatents.com Job Board

Thanks again for your help in supporting StemCellPatents.com.

Media Partnerships (NEW)

(BETA)