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Hello ,

Really neat patent issued last week, #7,501,281, which teaches how to induce self renewal without differentiation of neural stem cells by treatment with thrombin and other agents.  The idea being that there are numerous inactive growth factors on these stem cells that can be activated with various proteolytic enzymes.  Another patent, #7,501,115, covers aspects of Cytori's closed systems for purification of adipose stem cells.

In the news, a study was published showing the migratory effect of SDF-1 on hair follicle progenitors.  This is interesting since usually SDF-1 is thought of primarily as being a chemoattractant for hematopoietic stem cells. Also in the news, a new video was put up describing the ability of allogeneic mesenchymal stem cells to treat rheumatoid arthritis in the collagen induced arthritis model.

 


Compositions, methods and kits related to thrombin, Notch signaling and stamatogenesis and growth of stem cells
 
 
Patent Number: 7,501,281

This patent covers means of generating pluripotent stem cells out of neural stem cells or neural crest stem cells.  This is accomplished through contacting the neural stem cell or neural crest stem cell with an agent chosen from the following: a) thrombin; b) soluble Jagged1; c) thrombin receptor activated peptide, or d) a...[Read More]

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  Hair stem cells migrate to SDF-1

Monday March 16th, 2009 @ 03:12:44 EST

Chicago IL-

An argument has been made that various current day therapeutic uses of stem cells that involve intravenous administration is that "you cant just inject stem cells intravenously and you will get tissue repair".  Obviously there are certain situations in which the tissue will not be repaired, however, this...[Read More]

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  RECENTLY ADDED PATENTS  
  Mammary stem cell marker (7,563,619)
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  Soft tissue repair and regeneration using postpartum-derived cells (7,560,276)
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  Compositions and methods for generating skin (7,560,275)
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  Method for reducing neuronal degeneration so as to ameliorate the effects of injury or disease (7,560,102)
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  Human cord blood derived unrestricted somatic stem cells (USSC) (7,560,280)
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  Human cord blood derived unrestricted somatic stem cells (USSC) (7,556,801)
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  Dedifferentiated, programmable stem cells of monocytic origin, and their production and use (7,553,663)
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  Stromal antigen-presenting cells and use thereof (7,553,661)
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  Directed in vitro differentiation of marrow stromal cells into neural cell progenitors (7,547,545)
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  Progenitor cells from wharton's jelly of human umbilical cord (7,547,546)
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  View all 1436 Stem Cell Patents on StemCellPatents.com  


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