Method of transplanting in a mammal and treating diabetes mellitus by administering a pseudo-islet like aggregate differentiated from a nestin-positive pancreatic stem cell
Patent Number: 6866843
Date of First Priority Issue: Monday December 6th, 1999
Date Issued: Tuesday March 15th, 2005
Assignee: Viacell, Inc. (Charlestown, MA
Inventors: Habener, Joel F. (Newton Centre, MA); Zulewski, Henryk (Basel, CH); Abraham, Elizabeth (Quincy, MA); Vallejo, Mario (Madrid, ES); Faustman, Denise L. (Weston, MA); Thomas, Melissa K. (Boston, MA)
From Class: Use
Comments: No comments
This patent teaches extraction of pancreatic stem cells based on expression of nestin...expansion of the cells into islet-like cells...and transplantation of the cells for treatment of diabetes.
The problem is how much expansion can one achieve? Since there is a SEVERE shortage of donor pancreas'. The other problem, of course, is the need for immune suppression.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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