This patent covers the use of the transcription factor Pax4 for identifying the number of pancreatic stem cells in an animal. This patent is useful for entities seeking to expand the number of pancreatic stem cells in vivo through administration of various compounds. One such example is the work by Transition Therapeutics utilizing gastrin with EGF for treatment of diabetes through inducing proliferation of endogenous pancreatic stem cells in vivo.
View this patent on the USPTO website.
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