This patent teaches how to generate artificial skin through culturing of stem cells in a three dimensional matrix. Artificial skin is very useful not only for burn patients, but also for in vitro testing of topical drug formulations. The invention uses a stromal cell preparation onto which melanocytes and keratinocytes are added.
This patent claims a three dimensional structure that can be grown in vitro using stromal cells, stem cells, and other cell types, for the generation of tissue. The structure can then be introduced in vivo either to function as an organ, or to assist the function of an existing body component.