The current patent covers various compositions of matter for manufacturing tissue sealants. The sealants covered contain various growth factors, either recombinantly produced and added, or added through activation of cells. The sealants described are potentially synergistic with stem cells for acceleration of wound healing.
This patent teaches how to grow specialized epithelial structures from stem cells such as cornea, gingiva, and ureters. Specific tissue culture conditions and media are provided for growing the stem cells and inducing their differentiation into the desired tissue.
This patent covers a matrix that is made of hyaluronic acid and hydrolyzed collagen, that can be used as a scaffold for in vitro three dimensional tissue generation, or can be seeded with stem cells and implanted in vivo.
This patent describes ways of growing tissue in space or under microgravity conditions. This patent could be used not only for generation of medically important implants, but also for production of various artificial meats and foods for astronauts to eat while in space.
This patent teaches the generation of three dimensional tissues through culture under microgravity conditions. This patent discloses several culture conditions, as well as scaffolds, that can be utilized for the generation of the three dimensional organ or organoid structure.
This patent teaches the three dimensional generation of artificial pancreatic grafts using a proprietary culture system that is described in detail.
This patent teaches how to generate three dimensional cultures of stem cells through the use of special metrices and TGF beta. The three dimensional cultures can be generated using a variety of stem cells including mesenchymal stem cells. The mesenchymal stem cells may be extracted from bone marrow, cord blood or other sources.
In this patent regarding bone marrow stem cell culture, Advanced Tissue Sciences continues their tour de force in three dimensional culture IP, through covering the use of three dimensional cultures for expanding bone marrow stem cells. Specifically, the patent teaches that stromal cells and a three dimensional matrix can be used for expansion of hematopoietic...
This patent teaches the use of stromal cells to support growth, proliferation, and differentiation of islet-like pancreatic structures after addition of pancreatic acinar cells to the culture. This technology can be a great basis for the numerous other stem cell technologies currrently available for islet regeneration.
This patent teaches the generation of artificial kidneys through culturing of various cells that comprise the functional kidney in a three dimensional stromal preparation. The patent may be used not only for addition of kidney stem cells, but can incorporate various types of adult and embryonic stem cells for generation of "younger" kidneys.