Patents (1436 Stem Cell Patents)

Class: 3D Culture/Scaffold (92)

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Cardiovascular components for transplantation and methods of making thereof

Patent Number: 6695879

This patent provides compositions of matter useful for the treatment of cardiac valve dysfunctions. The compositions may be seeded with stem cells, or may be implanted as scaffolds that naturally become cellularized.

Inventor: Bell, Eugene (Boston, MA)
Assignee: TEI Biosciences, Inc. (Boston, MA)
Date of First Priority Issue: Tuesday October 20th, 1998

Method and device for preparing a dental implant by immersion in a culture of mesenchymal cells

Patent Number: 6589525

This patent teaches how to use various cells, including stem cells, for generation of a dental implant.

Inventor: Gault, Philippe (Orleans, FR)
Assignee: Societe Anonyme Natural Implant (Brest, FR)
Date of First Priority Issue: Tuesday October 13th, 1998

Composites for tissue regeneration and methods of manufacture thereof

Patent Number: 6454811

This patent provides various engineering techniques and devices for generation of artificial tissue from biological sources in vitro and in vivo. Specific material and ways of manipulating the materials to design cellular substrates and shape inducing structures are disclosed.

Inventors: Sherwood, Jill K. (Princeton, NJ); Griffith, Linda G. (Cambridge, MA); Brown, Scott (Princeton, NJ)
Assignee: Massachusetts Institute of Technology (Cambridge, MA); Therics, Inc. (Princeton, NJ)
Date of First Priority Issue: Monday October 12th, 1998

Resorbable scaffolds to promote cartilage regeneration

Patent Number: 6530956

This patent teaches how to make scaffolds that can be implanted in order to promote healing and regeneration of injured cartilage. Chondrocytes and/or mesenchymal stem cells may be used along with this invention.

Inventor: Mansmann, Kevin A. (Paoli, PA
Assignee: Unknown Assignee(s)
Date of First Priority Issue: Thursday September 10th, 1998

Tissue transplant coated with biocompatible biodegradable polymer

Patent Number: 6551355

This patent covers various biocompatible coating compositions that in one embodiment are used to decrease immunogenecity of bone grafts.

Inventors: Lewandrowski, Kai-Uwe (Brookline, MA); Bondre, Shrikar (Malden, MA); Trantolo, Debra J. (Princeton, MA); Cattaneo, Maurice V. (Quincy, MA); Gresser, Joseph D. (Brookline, MA); Wise, Donald L. (Belmont, MA)
Assignee: Cambridge Scientific, Inc. (Cambridge, MA)
Date of First Priority Issue: Friday August 14th, 1998

Culture vessel for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using same

Patent Number: 6080581

This patent covers a method of generating three dimensional tissues in culture. The culture system allows for continuous addition of media and growth factors as well as escape of waste products.

Inventors: Anderson, Charles Daniel (Houston, TX); Dodd, Charlie W. (Seabrook, TX)
Assignee: Unknown Assignee(s)
Date of First Priority Issue: Thursday July 2nd, 1998

Guided development and support of hydrogel-cell compositions

Patent Number: 6171610

This patent covers hydrogels that may be used in combination with stem cells for the generation of various artificial tissues.

Inventors: Vacanti, Charles A. (Uxbridge, MA); Vacanti, Joseph P. (Winchester, MA); Vacanti, Martin P. (Westborough, MA)
Assignee: University of Massachusetts (Boston, MA); The Children's Medical Center Corporation (Boston, MA)
Date of First Priority Issue: Friday April 24th, 1998

Guided development and support of hydrogel-cell compositions

Patent Number: 6027744

This patent covers ways generating tissue implants and artificial tissues in vitro for in vivo implantation.

Inventors: Vacanti, Charles A. (Worcester, MA); Vacanti, Joseph P. (Worcester, MA)
Assignee: University of Massachusetts Medical Center (Boston, MA); The Children's Medical Center Corporation (Boston, MA)
Date of First Priority Issue: Friday April 24th, 1998

Reversible gelling culture media for in-vitro cell culture in three-dimensional matrices

Patent Number: 6103528

This patent teaches how to make a tissue culture media which gells upon treatment or exposure to specific conditions. The advantage of this is that cells can be added when the media is liquid, and then the gelling characteristic can be used for the formation of specially shaped structures, structures which can subsequently be implanted.

Inventors: An, Yuehuei H. (Charleston, SC); Mironov, Vladimir A. (Mt. Pleasant, SC); Gutowska, Anna (Richland, WA)
Assignee: Battelle Memorial Institute (Richland, WA); Medical University of South Carolina (Charleston, SC)
Date of First Priority Issue: Friday April 17th, 1998

Cell-culture and polymer constructs

Patent Number: 6637437

This patent provides novel cellular "fillers" that are generated in culture specifically for the patient, and administered during head and neck surgery in order to "fill the gap".

Inventors: Hungerford, David S. (Cockeysville, MD); Frondoza, Carmelita G. (Woodstock, MD); Shikani, Alan H. (Ruxton, MD); Domb, Abraham J. (Efrat, IL)
Assignee: Johns Hopkins University (Baltimore, MD); Chondros, Inc. (Baltimore, MD)
Date of First Priority Issue: Wednesday April 8th, 1998

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