Class: 3D Culture/Scaffold (92)
Patent Number: 6695879
This patent provides compositions of matter useful for the treatment of cardiac valve dysfunctions. The compositions may be seeded with stem cells, or may be implanted as scaffolds that naturally become cellularized.
Inventor: Bell, Eugene (Boston, MA)
Assignee: TEI Biosciences, Inc. (Boston, MA)
Date of First Priority Issue: Tuesday October 20th, 1998
Patent Number: 6589525
This patent teaches how to use various cells, including stem cells, for generation of a dental implant.
Inventor: Gault, Philippe (Orleans, FR)
Assignee: Societe Anonyme Natural Implant (Brest, FR)
Date of First Priority Issue: Tuesday October 13th, 1998
Patent Number: 6454811
This patent provides various engineering techniques and devices for generation of artificial tissue from biological sources in vitro and in vivo.
Specific material and ways of manipulating the materials to design cellular substrates and shape inducing structures are disclosed.
Inventors: Sherwood, Jill K. (Princeton, NJ); Griffith, Linda G. (Cambridge, MA); Brown, Scott (Princeton, NJ)
Assignee: Massachusetts Institute of Technology (Cambridge, MA); Therics, Inc. (Princeton, NJ)
Date of First Priority Issue: Monday October 12th, 1998
Patent Number: 6530956
This patent teaches how to make scaffolds that can be implanted in order to promote healing and regeneration of injured cartilage. Chondrocytes and/or mesenchymal stem cells may be used along with this invention.
Inventor: Mansmann, Kevin A. (Paoli, PA
Assignee: Unknown Assignee(s)
Date of First Priority Issue: Thursday September 10th, 1998
Patent Number: 6551355
This patent covers various biocompatible coating compositions that in one embodiment are used to decrease immunogenecity of bone grafts.
Inventors: Lewandrowski, Kai-Uwe (Brookline, MA); Bondre, Shrikar (Malden, MA); Trantolo, Debra J. (Princeton, MA); Cattaneo, Maurice V. (Quincy, MA); Gresser, Joseph D. (Brookline, MA); Wise, Donald L. (Belmont, MA)
Assignee: Cambridge Scientific, Inc. (Cambridge, MA)
Date of First Priority Issue: Friday August 14th, 1998
Patent Number: 6080581
This patent covers a method of generating three dimensional tissues in culture. The culture system allows for continuous addition of media and growth factors as well as escape of waste products.
Inventors: Anderson, Charles Daniel (Houston, TX); Dodd, Charlie W. (Seabrook, TX)
Assignee: Unknown Assignee(s)
Date of First Priority Issue: Thursday July 2nd, 1998
Patent Number: 6171610
This patent covers hydrogels that may be used in combination with stem cells for the generation of various artificial tissues.
Inventors: Vacanti, Charles A. (Uxbridge, MA); Vacanti, Joseph P. (Winchester, MA); Vacanti, Martin P. (Westborough, MA)
Assignee: University of Massachusetts (Boston, MA); The Children's Medical Center Corporation (Boston, MA)
Date of First Priority Issue: Friday April 24th, 1998
Patent Number: 6027744
This patent covers ways generating tissue implants and artificial tissues in vitro for in vivo implantation.
Inventors: Vacanti, Charles A. (Worcester, MA); Vacanti, Joseph P. (Worcester, MA)
Assignee: University of Massachusetts Medical Center (Boston, MA); The Children's Medical Center Corporation (Boston, MA)
Date of First Priority Issue: Friday April 24th, 1998
Patent Number: 6103528
This patent teaches how to make a tissue culture media which gells upon treatment or exposure to specific conditions. The advantage of this is that cells can be added when the media is liquid, and then the gelling characteristic can be used for the formation of specially shaped structures, structures which can subsequently be implanted.
Inventors: An, Yuehuei H. (Charleston, SC); Mironov, Vladimir A. (Mt. Pleasant, SC); Gutowska, Anna (Richland, WA)
Assignee: Battelle Memorial Institute (Richland, WA); Medical University of South Carolina (Charleston, SC)
Date of First Priority Issue: Friday April 17th, 1998
Patent Number: 6637437
This patent provides novel cellular "fillers" that are generated in culture specifically for the patient, and administered during head and neck surgery in order to "fill the gap".
Inventors: Hungerford, David S. (Cockeysville, MD); Frondoza, Carmelita G. (Woodstock, MD); Shikani, Alan H. (Ruxton, MD); Domb, Abraham J. (Efrat, IL)
Assignee: Johns Hopkins University (Baltimore, MD); Chondros, Inc. (Baltimore, MD)
Date of First Priority Issue: Wednesday April 8th, 1998