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Hello manoj kumar valluru,

Last week a population of Oct4A positive stem cell-like cells were described in healthy and cancers prostates.  The more undifferentiated the prostate cancer cells were, the higher number of these cells were present.  This was interesting since these cells did not express "conventional" cancer stem cell markers such as CD133 and the drug efflux pump.

A patent #7,459,541 was issued on fusion proteins that specifically bind damaged tissue.  These are fusions between a specific domain of vWF and various growth factors already in clinical use.  This is an interesting one to look into for commercialization.

Another patent of interest, #7,459,152, was issued covering the use of erythropoietin to augment stem cell/neural transplants for treatment of Parkinson's.

Note: Next week's newsletter will be delivered on Tuesday.

 
 


Matrix-targeted fusion polypeptides for tissue regeneration and wound healing
 
 
Patent Number: 7,459,541

This patent covers a series of fusion proteins that are generated with selectively to bind collagen.  The inventors believe that since various forms of collagen are exposed during injury, the specific targeting of "repair" proteins to the injuried tissue will augment the healing process. 

Specifically the inventors...[Read More]

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  Possible Prostate Cancer Stem Cell

Sunday December 7th, 2008 @ 16:13:57 EST

Buffalo, New York -

The tumor stem cell concept implies a small self-renewing population of cells in a tumor mass is responsible for maintaining the bulk of the tumor which comprises primarily of differentiated cells.  This was demonstrated by O'Brien et al in the case of colon cancer in which only the small, quiescent, CD133 cells...[Read More]

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Stem Cells World Congress

The Stem Cell Meeting 

The 3rd Annual Stem Cells World Congress (20-22 January 2009)
The Stem Cell Meeting (March 2009)

 


  RECENTLY ADDED PATENTS  
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  Method for reducing neuronal degeneration so as to ameliorate the effects of injury or disease (7,560,102)
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  Human cord blood derived unrestricted somatic stem cells (USSC) (7,560,280)
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  Human cord blood derived unrestricted somatic stem cells (USSC) (7,556,801)
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  Dedifferentiated, programmable stem cells of monocytic origin, and their production and use (7,553,663)
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  Stromal antigen-presenting cells and use thereof (7,553,661)
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  Directed in vitro differentiation of marrow stromal cells into neural cell progenitors (7,547,545)
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  Progenitor cells from wharton's jelly of human umbilical cord (7,547,546)
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