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Hello manoj kumar valluru,

A publication in the Journal of Immunology co-authored by University of Western Ontario and Medistem Inc's Thomas Ichim successfully used third-party bone grafts to prevent acute antibody mediated immune rejection in an aggressive cardiac transplant model, possibly through mesenchymal stem cells.  The immune modulatory component was radioresistant and bone marrow mononuclear cells had no effect. 

Novocell scored another patent victory, # 7,534,608, covering about 394 ways of making insulin secreting cells from ES cells. This adds to Novocell's uncomparable IP portfolio that extends to the endoderm itself !

Another patent was issued in the area of diabetes, #7,537,756 covering ways of expanding donor islets and islet-like cells for allo or xeno transplantation. 

 


Methods of producing pancreatic hormones
 
 
Patent Number: 7,534,608

The company Novocell (merged from Cythera, BresaGen, and Novocell) has been strategically developing an IP portfolio covering numerous aspects of treating diabetes. 

Having IP on endoderm, as well as encapsulation technologies, the company recently was issued the current patent covering generation...[Read More]

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  Free bone allograft prevents acute immune reaction

Tuesday May 26th, 2009 @ 22:40:47 EST

London, Canada -

Antibody-mediated acute vascular rejection (AVR) is a major problem in organ transplantation.  The C3H to BALB/c heterotopic (second heart) cardiac transplant model resembles the human condition of AVR.  When recipients are given a course of the conventionally used immune suppressant agent cyclosporin A, grafts...[Read More]

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