Patents (1436 Stem Cell Patents)

Class: Expansion (424)

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Stem cell proliferation factor

Patent Number: 5981708

This patent covers a cytokine whose modern name is not known from reading the patent. The cytokine is capable of stimulating expansion of CD34+ human hemapoietic stem cells.

Inventors: Lawman, Michael J. P. (Gainesville, FL); Lawman, Patricia D. (Gainesville, FL); Denslow, Nancy D. (Gainesville, FL)
Assignee: University of Florida (Gainesville, FL)
Date of First Priority Issue: Thursday October 6th, 1983

Method for in vitro culture of mammalian cells

Patent Number: 5223428

This patent teaches methods of culturing and expanding cells, including stem cells, through a unique culture system that uses hollow fiber technology. Since tissue culture is usually performed under static conditions and very derived from the in vivo situation, numerous failures to expand stem cells can be explained. The culture system of this invention seeks to provide a more in vivo like...

Inventor: Rose, Sam (San Francisco, CA)
Assignee: Baxter International Inc. (Deerfield, IL)
Date of First Priority Issue: Tuesday December 14th, 1982

Enhanced growth medium and method for culturing human mammary epithelial cells

Patent Number: 4423145

This patent covers ways of growing mammary epithelial tissue in vitro. It teaches that such cells can be grown through dissociating stromal cells using enzymez and mechanical means so as to obtain a population of clumps of epithelial cells. The epithelial cells are then grown in a conditioned media that is either conditioned by human fetal intestine epithelial cells or human bladder...

Inventors: Stampfer, Martha R. (Oakland, CA); Smith, Helene S. (Oakland, CA); Hackett, Adeline J. (Orinda, CA)
Assignee: Unknown Assignee(s)
Date of First Priority Issue: Sunday July 5th, 1981

Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein

Patent Number: 5,728,581

This patent provides bioreactors and specific culture conditions for the in vitro and ex vivo expansion of hematopoietic stem cells. The patent discloses cytokines, oxygen tensions, and nutrients useful for expansion of cells.

Inventors: Schwartz, Richard Merrill (San Mateo, CA); Tucker, Sean Newton (San Francisco, CA); Chary, Srikanth Ranga (Fremont, CA); Kuo, Suzanne Chang (Cupertino, CA)
Assignee: Systemix, Inc. (Palo Alto, CA)
Date of First Priority Issue: Tuesday January 1st, 1980

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