Class: Administration (73)
Methods and compositions for correction of cardiac conduction disturbances
Patent Number: 7,494,644It is known that bone marrow stem cells are mobilized after heart injury such as infarct, with presumable therapeutic effects mediated by the stem cells in terms of stimulating angiogenesis or even integrating into the damaged myocardium and transdifferentiating into de novo cardiomyocytes.
One...
Transluminal application of adult stem cells for body organ tissue repair
Patent Number: 7,452,532Stem cell therapy for treatment of myocardial infarctions has demonstrated some benefit, including in double blind trials. Although the exact mechanism of action is unknown, some groups suggest that bone marrow stem cells can differentiate directly into new cardiomyocytes, whereas others believe the injected stem cells release...
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Method of transluminal application of myogenic cells for repair or replacement of heart tissue
Patent Number: 6805860This patent appears to cover the tempory occlusion of a vessel so that stem cells can be administered for repair of the injured organ. This patent has the potential to cover various clinical applications of stem cell therapies, especially for myocardial infarction that use a balloon stent to localize the stem cells into the infarct related artery.
Cell delivery system comprising a fibrous matrix and cells
Patent Number: 6790455This patent teachs cell delivery matrices that can be used for localized administration of stem cells into an area of need. The matrices disclosed are biocompatible and biodegradable. The patent is owned by a non-for-profit entity and appears to be available for licensing.
Medicinal implant and device and method for loading and delivering implants containing drugs and cells
Patent Number: 6648849This patent covers a medical device that can be used for administering stem cells together with various polymers and depot-like formulations into a host. The administration of stem cells together with growth factors is useful since this can allow the stem cells to remain in an "activated" state and accelerate their process of interacting with the host cells.
Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications
Patent Number: 6607501This patent teaches ways to continously perfuse a cell culture with plasma from a patient by performing a specialized "in vivo" plasmapheresis.
Resorbable posterior spinal fusion system
Patent Number: 7074239This invention is useful for entities interested in inducing spinal fusion, primarily for patients with lower back pain. The invention covers a medical implant that can be used to deliver various stem cell and progenitor cell chemoattractants, as well as morphogens, in order to accelerate healing and efficient fusion of vertebrae.
Implanting neural progenitor cells derived for human embryonic stem cells
Patent Number: 7011828This patent is a owned by the embryonic stem cell powerhouse, ES International from Singapore. The patent covers a method of administration of embryonic stem cells that have been differentiated into neuron-like cells. The invention contains one independent claim, specifically covering: "a method of administration of stem cell derived neural progenitors" but the neural progenitors are...
Percutaneous epicardial injection
Patent Number: 6659950As stem cell therapy advances, it becomes more and more important to develop methods of administering the stem cells. In this particular invention a medical device is provided that can inject stem cells, as well as growth factors and other cells, into the epicardium. This of course is useful for many cardiac conditions.
Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
Patent Number: 6884428This patent covers scaffolds that may be administered in vivo so that stem cells and progenitor cells attach to the scaffold and form functional tissue. Alternatively, the patent teaches that such scaffolds may be used in vitro so that cells form a functional tissue in vitro, which is then administered in vivo. Specific tissues that are described for use in the context of the current scaffold...