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Patents (1436 Stem Cell Patents)

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Class: Administration (73)

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Cells or tissue attached to a non-degradable filamentous matrix encapsulated by a semi-permeable membrane

Patent Number: 6303136

This teaches novel ways of encapsulating cells so that the immune system of the host does not reject them.

Inventors: Li, Rebecca (Needham, MA); Rein, David (Providence, RI)

Assignee: Neurotech S.A. (Evry, FR)

Date of First Priority Issue: Monday April 13th, 1998

Method for fabricating cell-containing implants

Patent Number: 6886568

This patent teaches the generation of cells with implantable biodegradable material through culture in vitro with materials of various compositions. The patent may be used for generation of artificial tissue, or for creating clusters of cells that may be implantable for treatment of disease. The patent is particularly aimed at inducing generation of chondrocytes ex vivo or in vitro for...

Inventors: Frondoza, Carmelita G. (Woodstock, MD); Fink, David J. (Baltimore, MD); Hungerford, David S. (Cockeysville, MD); Shikani, Alan H. (Ruxton, MD)

Assignee: The Johns Hopkins University (Baltimore, MD); Chrondros, Inc. (Baltimore, MD)

Date of First Priority Issue: Thursday April 9th, 1998

Polymer constructs

Patent Number: 6514522

This patent provides compositions of matter for administration of cells and cytokines into a host. The compositions are various polymers that are biodegradable, but can serve as delivery systems.

Inventor: Domb, Abraham J. (Efrat, IL)

Assignee: Chondros, Inc. (Towson, MD)

Date of First Priority Issue: Wednesday April 8th, 1998

Molecules that home to various selected organs or tissues

Patent Number: 6933281

This patent teaches the use of peptides that have the ability to home to specific tissues. Such homing peptides may be used to deliver drugs or therapeutic agents, as well as (conceptually) to administer activators of stem cells. The patent has 4 independent claims: - A lymph node homing peptide which is PTCAYGWCA (SEQ ID NO: 336). - A conjugate...

Inventors: Ruoslahti, Erkki (Rancho Santa Fe, CA); Pasqualini, Renata (Solana Beach, CA)

Assignee: The Burnham Institute (San Diego, CA)

Date of First Priority Issue: Friday March 13th, 1998

Bioabsorbable breast implant

Patent Number: 6881226

This patent covers a breast implant that eventually resorbs and is replaced by endogenous tissue. The patent has claims covering not only the use for cosmetic reasons, but also for administration of therapeutic agents.

Inventors: Corbitt, Jr., John D. (Palm Springs, FL); Leonetti, Lori A. (Delray Beach, FL)

Assignee: Unknown Assignee(s)

Date of First Priority Issue: Wednesday March 11th, 1998

Devices for cloaking transplanted cells

Patent Number: 6368612

This patent covers a device that can be implanted so as to protect the cells inside the device from immune mediated rejection. This is particularly useful for stem cell therapy and therapy with cells that are differentiated from stem cells because it would allow for the use of one cell source in all people. The device is also useful for transplantation of islet cells that are xenogeneic...

Inventors: Lanza, Robert P. (Clinton, MA); Chick, William (Wellesley, MA)

Assignee: Biohybrid Technologies LLC (Shrewsbury, MA)

Date of First Priority Issue: Friday December 12th, 1997

Membrane for in guided tissue regeneration

Patent Number: 6752834

Disclosed is a matrix that is useful for administration of living stem cells particularly for treatment of bone or cartilage injuries. The matrix is comprised primarily of collagen II and is compatible with a variety of stem cell technologies. This patent is useful for numerous applications.

Inventors: Geistlich, Peter (Stanstaad, CH); Eckmayer, Zdenek (Weinheim, DE); Schlosser, Lothar (Darmstadt, DE)

Assignee: Ed Geistlich Soehne AG Fuer Chemische Industrie (CH)

Date of First Priority Issue: Friday October 10th, 1997

Method and system for myocardial infarction repair

Patent Number: 7031775

This patent covers and implantable system made of cells, genes, other agents, together wtih a device that elecronically stimulates the cells. Specifically, the patent has 1 independent claim which covers a method of repairing the patient's myocardium through administration of a "cell repopulating source" and an "electrical stimulation device".

Inventors: Soykan, Orhan (Shoreview, MN); Donovan, Maura G. (St. Paul, MN)

Assignee: Medtronic, Inc. (Minneapolis, MN)

Date of First Priority Issue: Friday July 11th, 1997

Stimulation, culture and preservation of pancreatic cells

Patent Number: 6479283

This patent covers a method of administering beta cells in a matrix that allows for enhanced viability, as well as insulin production.

Inventors: M.ang.nsson, Per (Sollentuna, SE); Lundin, Tomas (Enkoping, SE); Busch, Christer (Troms.o slashed., SE)

Assignee: Ascendia AB (Sollentuna, SE)

Date of First Priority Issue: Tuesday March 18th, 1997

System for the in vivo delivery and expression of heterologous genes in the bone marrow

Patent Number: 6008035

This patent covers a method of generating viruses that are useful for transfection in living beings. Specifically the viral approaches can be used to target bone marrow stem cells.

Inventors: Johnston, Robert E. (Chapel Hill, NC); Davis, Nancy L. (Chapel Hill, NC); Simpson, Dennis A. (Pittsboro, NC)

Assignee: The University of North Carolina at Chapel Hill (Chapel Hill, NC)

Date of First Priority Issue: Wednesday February 19th, 1997

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