Patents (1436 Stem Cell Patents)

Class: Administration (73)

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Method and device for myogenesis and angiogenesis of the heart

Patent Number: 6551338

This patent covers ways of entering the myocardium through transthoracic means in order to administer angiogenic stimuli, which may include stem cells, or activators of stem cells that are associated with angiogenesis. The patent also discloses various administration devices.

Inventors: Chiu, Ray Chu-Jeng (Montreal, CA); Lachapelle, Kevin (Westmount, CA)
Assignee: McGill University (Montreal, CA)
Date of First Priority Issue: Wednesday September 1st, 1999

Foam composite for the repair or regeneration of tissue

Patent Number: 6306424

This patent provides various compositions of matter for making foam implants that can be used to deliver cells into a host.

Inventors: Vyakarnam, Murty N. (New York, NY); Zimmerman, Mark C. (East Brunswick, NJ); Scopelianos, Angelo George (Whitehouse Station, NJ); Chun, Iksoo (Flemington, NJ); Melican, Mora C. (Bridgewater, NJ); Bazilio, Clairene A. (Plainfield, NJ); Roller, Mark B. (Nor
Assignee: Ethicon, Inc. (Somerville, NJ)
Date of First Priority Issue: Wednesday June 30th, 1999

Drug releasing biodegradable fiber for delivery of therapeutics

Patent Number: 7033603

This patent relates to ways of delivering drugs (for example stem cell stimulating agents) to specific anatomical areas using an implantable, biodegradible approach. Specifically, the patent has 4 independent claims, the first 3 cover a delivery composition, and the 4th covers a scaffold.

Inventors: Nelson, Kevin D. (Arlington, TX); Crow, Brent B. (Fort Worth, TX)
Assignee: Board of Regents The University of Texas (Austin, TX)
Date of First Priority Issue: Tuesday June 8th, 1999

Intramyocardial injection of autologous bone marrow

Patent Number: 7097832

This patent is useful for the induction of collateral blood vessel formation (for example angiogenesis) in ischemic tissue. There are numerous conditions that may benefit from induction of said collateral blood vessel formation. For example ischemia of the various organs may be treated using this patent. The patent overall teaches the use of autologous bone marrow cells, either ex vivo...

Inventors: Kornowski, Ran (Ramat hasharon, IL); Fuchs, Shmuel (Rockville, MD); Epstein, Stephen E. (Rockville, MD); Leon, Martin B. (New York, NY)
Assignee: Myocardial Therapeutics, Inc. (San Diego, CA)
Date of First Priority Issue: Tuesday March 30th, 1999

Filamentary means for introducing agents into tissue of a living host

Patent Number: 6884427

This patent teaches a method of administering cells, including stem cells, through use of a filament-type object. The object has a solid core and an outside sheath that is porous and to which cells can be attached to before administration. The invention teaches that hair follicle cells, cells that have been encapsulated, and cells that have been genetically engineered can be...

Inventor: Barrows, Thomas H. (Austell, GA)
Assignee: Aderans Research Institute, Inc. (Beverly Hills, CA)
Date of First Priority Issue: Monday February 8th, 1999

Population of undifferentiated neural, endocrine or neuroendocrine cells in a hydrogel support

Patent Number: 7,470,425

There are many patents on stem cells, or populations of stem cells, or matrices for their delivery.  This patent is interesting because it is a sort of a "hybrid patent".  It is neither a patent on a matrix, or a patent on a cell.   

This patent covers a population of...

Inventors: Vacanti; Charles A. (Uxbridge, MA), Vacanti; Joseph P. (Winchester, MA), Vacanti; Martin P. (Manhattan, KS)
Assignee: VBI Technologies, L.L.C. (Houston, TX)
Date of First Priority Issue: Wednesday November 25th, 1998

Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same

Patent Number: 6630457

This patent teaches new compositions of matter based on hyaluronic acid that are useful for the administration of stem cells.

Inventors: Aeschlimann, Daniel (Madison, WI); Bulpitt, Paul (Madison, WI)
Assignee: Orthogene LLC (Sausalito, CA)
Date of First Priority Issue: Friday September 18th, 1998

Methods for implanting cells

Patent Number: 6579313

The problem with various grafts and prosthesis is that the body starts reacting to them, either through restenosis, or complement activation, or thrombosis. This patent teaches unique ways to generate grafts and prosthetics through the implantation of stem cells and/or other cellular components in the structure to be introduced into the body.

Inventors: Dzau, Victor J. (Newton, MA); Pratt, Richard E. (Newton, MA); Mann, Michael J. (Newton, MA); Ehsan, Afshin (Boston, MA); Griese, Daniel P. (Boston, MA)
Assignee: The Bringham and Women's Hospital (Boston, MA)
Date of First Priority Issue: Friday July 10th, 1998

Methods for implanting cells

Patent Number: 6352555

This patent provides methods and devices for administration of cells, including stem cells, via various prosthetic devices.

Inventors: Dzau, Victor J. (Newton, MA); Pratt, Richard E. (Newton, MA); Mann, Michael J. (Newton, MA); Ehsan, Afshin (Boston, MA); Griese, Daniel P. (Boston, MA)
Assignee: The Brigham and Womens Hospital, Inc. (Boston, MA)
Date of First Priority Issue: Friday July 10th, 1998

Implantable system with drug-eluting cells for on-demand local drug delivery

Patent Number: 6206914

This patent covers the use of cells, including stem cells and derivatives, for producing certain drugs or proteins specifically upon stimulation. Stimulation may be electrical, mechanical, or chemical.

Inventors: Soykan, Orhan (New Brighton, MN); Donovan, Maura G. (St. Paul, MN) )
Assignee: Medtronic, Inc. (Minneapolis, MN
Date of First Priority Issue: Thursday April 30th, 1998

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