Class: Administration (73)
System for the in vivo delivery and expression of heterologous genes in the bone marrow
Patent Number: 5811407This patent teaches the transfection of bone marrow stem cells using a new type of vector. The vector disclosed is an alphavirus vector. Transfection by alphavirus has been performed in numerous situations and is actually in clinical trials.
Regeneration and augmentation of bone using mesenchymal stem cells
Patent Number: 6541024This patent teaches ways of generating bone tissue using mesenchymal stem cells that are placed into a special matrix. In one embodiment, the matrix and the mesenchymal stem cells are administered into an area of bone injury.
Systems and methods of use for delivering beneficial agents for revascularizing stenotic bypass grafts and other occluded blood vessels and for other purposes
Patent Number: 6569147This patent teaches methods of administering cells and fluids in order to prevent inflammation and induce regeneration in areas of stent placement.
Apparatus and methods for preparing an implantable graft
Patent Number: 6049026This patent provides methods of administering stem cells after differentiating them into bioartificial bone.
Regeneration and augmentation of bone using mesenchymal stem cells
Patent Number: 6863900Biocompatible crosslinked composition
Patent Number: 7,176,256Surgical adhesions cause excess fibrosis in an area that has been surgically manipulated. Adhesions are a major cause of post operative morbidity. In this patent biodegradable polymers are disclosed that are useful for covering post surgical areas in order to inhibit formation of adhesions. Essentially, the patent covers crosslinked polymer compositions in which the first synthetic polymer...
Methods and compositions of growth control for cells encapsulated within bioartificial organs
Patent Number: 5833979Lets imagine that one wanted to implant embryonic stem cells into a human. The first concern would be rejection by allogeneic immunity. To overcome this one could immune suppress, which is not desirable, or one could encapsulate the cells. If the cells are encapsulated but start proliferating, then they can either die or break through the encapsulation device. This patent teaches the use of...
Methods and compositions of growth control for cells encapsulated within bioartificial organs
Patent Number: 5853717This patent teaches ways of encapsulating stem cells and their derivatives. It provides various means and devices for the generation of artificial organs. Additionally, the patent teaches how to optimize the viability of the stem cells in the artificial organ.
Biomatrix for soft tissue regeneration
Patent Number: 5855619This patent provides various compositions of matter that are useful for the administration of stem cells in order to heal or regenerate soft tissue.
Matrix for the manufacture of autogenous replacement body parts
Patent Number: 5906827Disclosed are a variety of devices and matrices that are useful for generation of artifical joints through the use of stem cells and differentiated cells.