Class: 3D Culture/Scaffold (92)
Device having a microporous membrane lined deformable wall for implanting cell cultures
Patent Number: 6479066This patent covers an implantable 3 dimensional matrix that takes the shape of the cavity it is administered in. This matrix is a great delivery system for introduction of various cell types into the host. In some ways this patent is useful for generation of compositions useful for the treatment of bone defects, livers, and other bodily structures.
Bioprosthetic heart valves
Patent Number: 6660260This patent coves a heart valve that secretes nitric oxide. This patent is useful for treatment of various diseases associated with valvular dysfunction such as aortic insufficiency and mitral stenosis. The roles of nitric oxide in the cardiovascular system range from vasodilation, to inhibition of apoptosis.
Porous tissue scaffoldings for the repair or regeneration of tissue
Patent Number: 6534084The importance of scaffolds in tissue engineering can not be understated. In this patent, various composition of matter, included foam-based and biodegradable scaffolds are provided.
Porous tissue scaffoldings for the repair or regeneration of tissue
Patent Number: 6365149This patent covers the composition of matter and use of a specialized foam that can be embedded with stem cells and inserted in vivo, or can be inserted in vivo with chemoattractants for stem cells so that the endogenous stem cells repopulate it.
Porous tissue scaffoldings for the repair of regeneration of tissue
Patent Number: 6333029This patent provides compositions of matter, and their uses, for generation of foams and various implantable structures that can function as scaffolds for the generation of artificial tissues.
Generation of viable cell active biomaterial patterns by laser transfer
Patent Number: 6905738This patent was included the 3d culture/scaffold section since it doesnt really seem to fit anywhere else. Essentially the patent teachs how to write on cells (including stem cells) using laser light. The patent has 1 independent claim, which is: A method for laser deposition comprising the steps of; providing one or more sources of laser energy that produce laser...
Mineralization and biological modification of biomaterial surfaces
Patent Number: 6767928This patent covers ways of altering biomaterials so that bone may be grown around them. Specifically useful is the application of such biomaterials as scaffolds around which stem cells can be grown in order to generate tissues that can be implanted.
Scaffold for tissue engineering cartilage having outer surface layers of copolymer and ceramic material
Patent Number: 6692761This patent covers scaffolds that can be seeded with cells and/or growth factors so as to promote regeneration of cartilage.
Method for vocal cord reconstruction
Patent Number: 6918396This invention is useful for repairing injuries to head and neck tissue through use of vertebrate-derived submucosa or basement membrane matrices as a graft for the regeneration and repair of said head and neck soft tissues. Specifically, it is known that a) The naturally-occurring extracellular matrix (ECM) of the small intestinal submucosa, as well as other vertebrate sources of...
Lymphoid tissue-specific cell production from hematopoietic progenitor cells in three-dimensional devices
Patent Number: 7,192,769The current invention teaches methods of generating 3-dimensional culture conditions for the expansion of lymphocytes out of hematopoietic stem cells. The invention specifically covers the production of T cells through the culture of a hematopoietic stem cell together with a lymphoid stromal element in the presence of an antigen presenting cell. Lymphoid stromal elements may be allogeneic...