Category: Hematopoietic (23)
Stromal-Like Environment Critical to Stem Cell Expansion
St. Louis, MO-
It is long been suggested that the appropriate imitation of in vivo microenvironments is critical to successful culture, expansion, and differentiation of stem cells.
In a paper which appeared in the Nov 9 online issue of Blood (Cytokine and integrin stimulation synergize to promote higher levels of GATA-2, c-myb, and CD34... Durham, North Carolina
Chute et al reported today that administration of mouse endothelial cells to irradiated B6 recipients was capable of accelerating hematopoietic reconstitution after sublethal and lethal irradiation.
In a paper entitled "Transplantation of vascular endothelial cells mediates the hematopoietic recovery and survival of lethally irradiated mice" published in today's... London UK
One of the major limitations of stem cell transplantation is the need to overcoming allogeneic barriers. The generation of stem cells from already differentiated tissue would significantly revolutionize the area of stem cell therapeutics.
In a paper published today (Abuljadayel et al. Infusion of autologous retrodifferentiated stem cells into patients with beta-thalassemia...
Endothelial Stimulation of Hematopoietic Engraftment
Clinical Trial of “Retro-Differentiated” Stem Cells: A Novel Way to Generate Autologous Stem Cells