Patents (1436 Stem Cell Patents)

Class: Extraction/Preservation (156)

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Compositions and methods of making embryonic stem cells

Patent Number: 6251671

This patent covers methods of generating spermatogonial stem cells. These stem cells may be used for a wide variety of regenerative purposes, as well, they appear similar in some ways to the cells generated by the company Primegen.

Inventors: Hogan, Brigid L. M. (Brentwood, TN); Zhao, Guang-Quan (Nashville, TN)
Assignee: Vanderbilt University (Nashville, TN)
Date of First Priority Issue: Wednesday February 28th, 1996

Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration

Patent Number: 6200606

This patent covers the use of adipose derived stem cells for the generation of cartilage and bones.

Inventors: Peterson, Dale R. (Carmel, IN); Nousek-Goebl, Nancy (Fishers, IN)
Assignee: DePuy Orthopaedics, Inc. (Warsaw, IN)
Date of First Priority Issue: Tuesday January 16th, 1996

Preservation of tissue during removal storage and implantation

Patent Number: 6207658

Disclosed are various formulations and chemicals in which cells and tissue can be stored for prolonged time periods.

Inventors: Simpkins, James W. (Gainesville, FL); Green, Pattie S. (Gainesville, FL); Gridley, Kelly E. (Gainesville, FL)
Assignee: University of Florida Research Foundation, Inc. (Gainesville, FL)
Date of First Priority Issue: Thursday January 11th, 1996

Stem cell factor receptor-(c-kit)-specific monoclonal antibody A3C6E2

Patent Number: 5808002

This patent covers the use of an antibody to c-kit for the quantification and extraction of hematopoietic stem cells. Since non-hematopoietic stem cells also express c-kit, this antibody may have other uses than originally contemplated.

Inventor: Buhring, Hans-Jorg (Tubingen, DE)
Assignee: Eberhard-Karls-Universitat Tubingen (Tubingen, DE)
Date of First Priority Issue: Wednesday January 10th, 1996

Human stem cell antigen 2

Patent Number: 6130061

This patent covers a new protein that is expressed on various types of stem cells. This protein can be used for purification of stem cells from tissue, or for assessment of stem cell populations in various in vitro culture systems.

Inventors: Ni, Jian (Rockville, MD); Yu, Guo-Liang (Darnestown, MD); Gentz, Reiner (Silver Spring, MD); Gocayne, Jeannine D. (Potomac, MD)
Assignee: Human Genome Sciences, Inc. (Rockville, MD)
Date of First Priority Issue: Thursday November 9th, 1995

Methods for preparing enriched human hematopoietic cell preparations

Patent Number: 6306575

This patent provides kits for negatively depleting a population of cells so that what remains is hematopoietic stem cells. Different variants of this kit are sold by the Canadian company StemCell Technologies.

Inventors: Thomas, Terry (Vancouver, CA); Lansdorp, Peter (Vancouver, CA)
Assignee: StemCell Technologies, Inc. (Vancouver, CA)
Date of First Priority Issue: Friday June 16th, 1995

Methods of obtaining compositions enriched for hematopoietic stem cells, antibodies for use therein, compositions derived therefrom and methods of use thereof

Patent Number: 6127135

This patent covers a novel marker of stem cells which the inventors call EM10. This patent is useful for identifying the stem cell content of a population of cells.

Inventors: Hill, Beth Louise (Mountain View, CA); Rozler, Elen (Mountain View, CA); Chen, Benjamin P. (Fremont, CA)
Assignee: Unknown Assignee(s)
Date of First Priority Issue: Wednesday June 7th, 1995

Myocardial grafts and cellular compositions

Patent Number: 6015671

This patent teaches how to extract specific cells from a population of stem cells that are differentiating.

Inventor: Field, Loren J. (Indianapolis, IN)
Assignee: Indiana University Foundation (Bloomington, IN)
Date of First Priority Issue: Wednesday June 7th, 1995

Methods of obtaining compositions enriched for hematopoietic stem cells, antibodies for use therein, compositions derived therefrom and methods of use thereof

Patent Number: 5814440

Disclosed are methods of purifying hematopoietic stem cells using the antibody EM10.

Inventors: Hill, Beth Louis (Mountain View, CA); Rozler, Elen (Mountain View, CA); Chen, Benjamin P. (Fremont, CA)
Assignee: Systemix, Inc. (Palo Alto, CA)
Date of First Priority Issue: Wednesday June 7th, 1995

Method of preparing hematopoietic stem cells with gp105-specific antibodies

Patent Number: 6083747

This patent discloses a new marker of hematopoietic stem cells. The marker can be used for isolation, purification, or identification of such stem cells.

Inventors: Wong, Peter M. C. (Gladwyne, PA); Chung, Siu-Wah (Gladwyne, PA); Han, Xiaodong (San Francisco, CA)
Assignee: Stemcell Therapeutics LLC (Bala Cynwyd, PA)
Date of First Priority Issue: Tuesday June 6th, 1995

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