Class: Extraction/Preservation (156)
Identification of blast cells in a leukocyte cell preparation
Patent Number: 5905031This patent covers ways of detecting blast cells from other types of cells using photometric means.
Isolated stromal cells and methods of using the same
Patent Number: 6974571The invention covers a way of introducing stem cells into a host in such a manner that the cells can be killed off if desired through administration of an agent that induces expression of a suicide gene. This is important since in some situations it is desired to have the exogenous stem cells in the body only for a limited period of time. Specifically, the invention has 2 independent claims...
FGFR3 as a marker for mesenchymal skeletal progenitor cells
Patent Number: 6517872This patent teaches ways of extracting mesenchymal stem cells that act as progenitors for various types of bone. The expression of the receptor for fibroblast growth factor-3 is used as the identifying marker.
High concentration white blood cells as a therapeutic product
Patent Number: 7,169,547This patent covers methods of preserving cord blood mononuclear cells. The approach taken here is focused on the collection and preservation of white blood cells from cord blood as a "therapeutic product". The cells appear to be stored in plasma from the same source as the donor and this may be one of the reasons why this patent was issued in light of the pre-existing
Methods for identifying fetal cells
Patent Number: 5750339Fetal to maternal trafficking of stem cells is a relatively undiscussed phenomena. This patent covers methods of detecting fetal cells in maternal circulation, in one embodiment through identification of cells expressing the immune suppressive molecule HLA-G
Method to produce novel embryonic cell populations
Patent Number: 6110739This patent covers generation of cells from embryonic stem cells, and subsequent immortalization of the generated cells. The generated cells may be semidifferentiated stem cells or precursor cells. Immortalization may be accomplished by transfection with the gene HOX 11.
Methods of obtaining compositions enriched for hematopoietic stem cells, compositions derived therefrom and methods of use thereof
Patent Number: 5677136This patent teaches that the protein CD59 may be used as a marker of hematopoietic stem cells both for identification, and also for purification.
Method of purifying a population of cells enriched for hematopoietic stem cells populations of cells obtained thereby and methods of use thereof
Patent Number: 5665557This patent covers the use of CDw109 for purification and identification of hematopoietic stem cells.
Neural cell protein marker RR/B and DNA encoding the same
Patent Number: 6066451This patent provides a marker for the identification of specific neural cells. This marker is useful for knowing the quantity and quality of neurons generated from various stem cell populations.
Method of selecting pluripotent hematopioetic progenitor cells
Patent Number: 5827742This patent takes advantage of the fact that early hematopoietic stem cells are usually CD34+ and quiescent. By treatment of CD34+ cells with cytotoxic agents that kill proliferating cells, a population of primitive stem cells may be obtained.