Class: Extraction/Preservation (156)
Use of nerve growth factor for the storage, culture or treatment of cornea
Patent Number: 6537808This patent covers the use of NGF for storing corneal samples, but also for use as a topical solution for the treatment of diseases associated with corneal dysfunction.
Molecular marker for muscle stem cells
Patent Number: 6337184This patent claims that expression of the anti-apoptotic gene bcl-2 can be used as a marker for stem cells of the muscle. The problem is that bcl-2 is an intracellular molecule, therefore it is difficult to selectively purify based on its expression. If a colourogenic substrate for bcl-2 can be discovered or already exists, this would greatly increase the value of the current patent.
Method of detecting hematopoietic progenitor cells
Patent Number: 5830701This patent provides devices that can quantify hematopoietic stem cell numbers from a pool of cells through non-immunological means.
Method of detecting hematopoietic progenitor cells
Patent Number: RE39,006This patent appears to cover a new method of detecting hematopoietic stem cells, without needing to use stem cell-specific markers. The patent seems to use some light and physical properties of the cells to distinguish between stem cells and non-stem cells. The patent has one issued claim which is: "A method for detecting or counting or both detecting and counting hematopoietic...
Composition and method for preserving progenitor cells
Patent Number: 7,112,653This patent covers peptides that inhibit hematopoietic stem cell proliferation, thereby allowing protection of these cells from chemotherapy or radiotherapy. This patent may conceptually be applicable to selectively inhibiting healthy stem cells while allowing leukemic stem cells to proliferate so that chemotherapy or radiotherapy may selectively kill the proliferating leukemic cells.
Composition and method for preserving progenitor cells
Patent Number: 6084060This patent discloses lectins and portions of the lectins that are capable of protecting various types of stem cells from death or inactivation.
Method of isolating mesenchymal stem cells associated with isolated megakaryocytes by isolating megakaryocytes
Patent Number: 5965436This patent teaches that mesenchymal stem cells in the bone marrow are sometimes found in attachment to megakaryocytes. The patent teaches that it is possible to extracted megakaryocytes from the bone marrow, using antibodies such as anti-CD41, and then from the megakaryocytes to de-attach the mesenchymal stem cells.
Antibody recognizing a small subset of human hematopoietic cells
Patent Number: 7,247,718This patent covers an antibody that binds CD34 cells called MG-1. This is a useful patent for people trying to circumvent Baxter's CD34 patent or Miltenyi's CD133.
Antibody recognizing a small subset of human hematopoietic cells
Patent Number: 6838282This is a patent for a unique stem cell marker that is recognized by the antibody MG-1. There are numerous stem cell markers in existence which are used for isolation of stem cell subtypes. The value of new stem cell markers is relatively high since the field is very populated. A patent such as the present one, if MG-1 has not been commercialized, can be used to position a new biotech...
Antigen found on a small subset of human hematopoietic cells which binds to monoclonal antibody MG1
Patent Number: 6242579This patent covers an antigen that is found on some types of hematopoietic stem cells. This antigen can be used for purification of hematopoietic stem cells by magnetic or flow cytometric means.