Class: Extraction/Preservation (156)
Purging of stem cell products
Patent Number: 6475481This patent covers ways of purging tumor cells from bone marrow stem cell grafts. Specifically, the patent teachs ways of selectively protecting the bone marrow through gene transfection, while allowing tumor cells to die. This patent is particularly suited for situations of autolous bone marrow transplants in cancer patients in order to allow for high levels of chemotherapy and/or...
Transfection, storage and transfer of male germ cells for generation of transgenic species and genetic therapies
Patent Number: 6734338This patent teaches how to transfect male germ stem cells in non-human mammals. This technology is useful for generation of a variety of animal models for laboratory experimentation. It is also useful for research companies who want to circumvent some of the transgenic patents today.
Cell separation using electric fields
Patent Number: 6589786This patent teaches how to utilize distinct electromagnetic properties of stem cells for their isolation. Additionally it teaches how to purge a population of stem cells from contaminating cancer cells.
Method of treating dopaminergic and GABA-nergic disorders
Patent Number: 7,138,492It is known that hedgehog proteins are important in specifying what cells give rise to what tissues during development. Others have patented using hedgehog proteins for stimulating insulin production. In this patent the inventors found a new use for hedgehog proteins besides their known role in embryogenesis. Initially, the...
Method of determining progenitor cell content of a hematopoietic cell culture
Patent Number: 6077708This patent teaches how to determine the number of stem cells in a tissue culture situation through assessing various metabolic properties of the tissue culture media.
Apparatus for extracting bone marrow
Patent Number: 6358252Usually bone marrow is extracted from the iliac crest of patients. In this patent a new device for extracting bone marrow is disclosed. The patent is useful for, intra alia, taking out bone marrow from the jaw bone of a subject that is undergoing dental surgery. If you thought root canals are painful, imagine this !
Methods for extracting bone marrow
Patent Number: 6110176This patent provides procedures and devices useful for harvesting bone marrow. In one embodiment the bone marrow is harvested from the jaw of the patient.
Apparatus for extracting bone marrow
Patent Number: 5913859This patent teaches methods and discloses devices, that are useful for the extraction of bone marrow stem cells from the jawbone of a patient.
Progenitor cell preservation factors and methods for and products of their use
Patent Number: 6991794This patent is directed to the stimulation of hematopoietic stem cell proliferation by use of a lectin called FRIL. The patent has 2 independent claims. The first is directed towards a pharmaceutical composition claiming some distinct sequences that bind glycosylated flt-3. The second is directed towards treatment, using the same sequences. There is a paper...
Lectin-derived progenitor cell preservation factor and methods of use
Patent Number: 6852321This patent teaches that certain lectins (sugar binding proteins) may be used for the preservation of progenitor cells and stem cells. It is not clear which property of the lectins is involved in the preservation. The concept that lectins may be used in stem cell preservation brings to mind old experiments in which the preferentially affinity of lectins to cancer cell membranes was...