Class: Extraction/Preservation (156)
Method for enriching adherent monocyte populations
Patent Number: 7,393,628Monocytes are generally known as the precursors to macrophages, cells involved in phagocytosing bacteria and injured tissue (thats why in Latin "Macrophage" apparently means "Big Eater").
However, in addition to the classical functions of monocytes, there is evidence to suggest that these cells are potent stimulators of
Buffy coat tube and float system and method
Patent Number: 7,329,534This patent covers a device that is capable of separating various cellular populations, or populations of particulate matter. Essentially, the device addresses the need for an easy to use, effective, and rapid method of collecting the "buffy coat" from a blood population, as well as cells within the buffy coat. The device purifies the cells using axial expansion of blood fluid components...
Antibodies isolating and/or identifying neuronal stem cells and method for isolating and/or identifying neuronal progenitor cells
Patent Number: 7,182,946Methods of purifying stem cells, as well as progenitor cell populations are well known in the art. Unfortunately, some of these methods have certain limitations, and as a result, there is always a great need to identify new ways of sometimes doing the same thing. For example, it is known that CD34 is a useful marker for hematopoietic stem cells. However, since the...
CD56 positive human adult pancreatic endocrine progenitor cells
Patent Number: 7,371,576The quest for a stem cell therapy for diabetes has led to the evaluation of numerous cellular sources ranging from embryonic stem cells, to bone marrow derived stem cells, to mesenchymal stem cells. One interesting method of expanding insulin producing cells is through extraction of pancreatic...
Method and apparatus for sorting biological cells with a MEMS device
Patent Number: 6838056This patent covers a medical device that is useful for purifying hematopoietic stem cells. The medical device selects stem cells but not contaminating cancer cells, and is therefore useful for treatment of cancer patients by purifying autologous stem cells before high dose chemotherapy so that the stem cells can be re-introduced in order to accelerate reconstitution of hematopoiesis.
Methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells
Patent Number: 7,247,477The patent covers generation of angiogenic cells from embryonic stem cells using a novel method. Specifically the patent covers a way to generate such angiogenic cells by: 1) culturing individual ES cells in an unaggregated state under conditions that induce differentiation into vasculagenic progenitors (the claim is not limited by what those conditions are!) 2) isolating cells...
Isolation tool for viable c-kit expressing cells
Patent Number: 7,285,413CD-117, otherwise known as c-kit, is the receptor for stem cell factor, a cytokine involved in stimulating a variety of stem cells to cycle. Although c-kit was originally described on hematopoietic stem cells, this receptor has recently been found on numerous stem cell types ranging from liver oval cells to pancreatic duct stem cells. Additionally, c-kit has been found on tumor stem...
Self-contained adipose derived stem cell processing unit
Patent Number: 7,390,484Adipose tissue is known to contain a variety of different cellular populations. For example, Medistem Inc (mdsm.ob) reported presence of immune suppressive T regulatory cells in adipose tissue that could potentially be useful for inhibiting autoimmunity.
Another type of cell found in adipose tissue is endothelial... Adipose derived stem cells have been very useful therapeutically for a variety of indications, at least from animal studies. For example, syngeneic adipose mesenchymal stem cells have been demonstrated to improve cardiac parameters in a porcine model of heart failure. Adipose derived cells have stimulated angiogenesis in models of 
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Systems and methods for treating patients with processed lipoaspirate cells
Patent Number: 7,501,115
Stem cell and dental pulp harvesting method and apparatus
Patent Number: 6767740Teeth are known to contain various cellular populations in the pulp, including stem cells. The idea of banking tooth stem cells is limited by the ease of extraction. This patent discloses various apparatus' that are easily used for the extraction of tooth stem cells.