Class: Extraction/Preservation (156)
Method of concentrating and separating dopaminergic neurons
Patent Number: 7,270,998Selection of cells with specific phenotypes is a critical part of the development of stem cell therapeutics. Several patents are issued on methods of selecting differentiated cells with a specific phenotype from a heterogenous population. In the current patent 5 independent claims are issued covering the isolation of dopamine producing cells by the selection of cells which have an active...
Method of identifying a neural progenitor cell by evaluating expression of daedalos
Patent Number: 6759201This patent covers a new marker for neural stem cells called Daedalos. It provides methods of using this marker for identifying and extracting neural stem cells. The neural stem cells can be used for treatment of a variety of neurological disorders such as Parkinsons, Alzheimers, etc.
Devices and methods for harvesting limbal stem cells
Patent Number: 6679898This patent provides a medical device and ways to use the device to extract corneal tissue and limbal stem cells from the eye of a donor.
Compositions for identification and isolation of stem cells
Patent Number: 6632620This patent provides an antibody that recognizes both epidermal stem cells, as well as prostate cancer cells.
Method of collecting placental stem cells
Patent Number: 7045148This patent is useful for entities seeking to extract additional CD34 stem cells from placenta than can be normally gathered by just letting the blood drip and collecting cord blood. This patent has one independent claim that covers, essentially perfusing the placenta with an anticoagulated solution after the cord blood has dripped out.
Method for purifying pluri-differentiated mesenchymal progenitor cells
Patent Number: 7,303,769This patent covers the extraction/purification of a type of mesenchymal stem cell. Specifically the invention claims removing macrophages from a Dexter culture, fractionating cells, and collecting from the factionated cells a stem cell population. The fractionation procedure may be performed by percoll gradient (a type of density gradient). The stem cells that are purified are called...
Antibody compositions for preparing enriched mesenchymal progenitor preparations
Patent Number: 6645727This patent covers the antibody kit that can be used for negatively depleting non-mesenchymal stem cell populations from a population of cells in order to obtain a substantially purified population of mesenchymal stem cells.
Compositions for identification and isolation of stem cells
Patent Number: 7,223,549This patent covers several antibodies that specifically bind ectodermally-derived stem cell but have weaker affinity for stem cells of mesodermal and endodermal origin. The antibodies seem to bind prostate and liver stem cells but not dermal stem cells. The antibodies are deposited with ATTC and are commercially available. Unfortunately, the ligand for the...
Making neural cells for human therapy or drug screening from human embryonic stem cells
Patent Number: 6833269Despite all the publicity of embryonic stem cell therapy, the fact that embryonic stem cells turn into cancer cells when inserted into a living organism suggests the very import need to understand and develop ways of manipulating them to differentiate into the tissue that is needed to be repaired. This patent teaches conditions for generating neural cells from embryonic stem cells through...
Method for the isolation of stem cells by immuno-labeling with HLA/MHC gene product marker
Patent Number: 6828145Classically hematopoietic stem cells are purified based on expression of markers such CD34 or c-kit. This patent teaches that hematopoietic stem cells can also be further purified by selecting cells that lack expression of MHC I. The lack of expression of class I may have to do with the presumed weaker immunogenecity of hematopoietic stem...