Class: 3D Culture/Scaffold (92)
Patent Number: 7,122,200
This patent covers ways of generating an artificial urinary tract through tissues engineering and culture of stem cells.
Inventors: Kropp; Bradley P. (Edmond, OK), Cheng; Earl Y. (Edmond, OK), Zhang; Yuan Yuan (Edmond, OK), Cowan; Rick (Oklahoma City, OK), Moore; Peter (Perry, OK)
Assignee: The Board of Regents of the University of Oklahoma (Norman, OK)
Date of First Priority Issue: Friday December 8th, 2000
Patent Number: 6696074
This patent teaches how to make scaffolds that are useful for subsequent seeding with stem cells and generating tissues. The scaffolds seem to be made from decellularized tissues, including fetal and xenogeneic (in some cases) sources.
Inventors: Dai, Jianwu (Boston, MA); Bell, Eugene (Boston, MA); Russakovsky, Vladimir (Boston, MA)
Assignee: TEI Biosciences, Inc. (Boston, MA)
Date of First Priority Issue: Monday December 4th, 2000
Patent Number: 6899915
Inventors: Yelick, Pamela C. (Concord, MA); Bartlett, John D. (Acton, MA); Vacanti, Joseph P. (Winchester, MA); Olsen, Bjorn R. (Milton, MA); Stashenko, Phillip (Medfield, MA)
Assignee: President and Fellows of Harvard College (Cambridge, MA); General Hospital Corporation (Boston, MA); Forsyth Dental Infirmary for Children, Inc. (Boston, MA)
Date of First Priority Issue: Wednesday November 29th, 2000
Patent Number: 7,335,230
One of the areas in which regenerative medicine has caused the most advancement is in repair of connective tissue injuries. The current patent addresses this area. Specifically, the patent covers an object that can be implanted and used as a substitute for a connective tissue.
The objected is made with a pair of bone anchors, with at least one filament connecting the bone achors at their...
Inventors: Goulet; Francine (Sainte-Foy, CA), Rancourt; Denis (Levis, CA), Cloutier; Rejean (Sillery, CA), Tremblay; Julie (Beauport, CA), Auger; Francois A. (Sillery, CA), Normand; Albert (Sainte-Foy, CA), German; Lucie (St-Augustin, CA), Lamontagne; Jean (St-Augus
Assignee: Universite de Montreal (Montreal, CA)
Date of First Priority Issue: Friday November 24th, 2000
Patent Number: 6730252
This patent covers generation of filaments that are useful for forming three dimensional scaffolds for tissue engineering using stem cells or precursor cells.
Inventors: Teoh, Swee Hin (Singapore 596504, SG); Hutmacher, Dietmar Werner (Singapore, SG); Tan, Kim Cheng (Singapore 524856, SG); Tam, Kock Fye (Singapore 730659, SG); Zein, Iwan (Singapore 448909, SG)
Assignee: Unknown Assignee(s)
Date of First Priority Issue: Wednesday September 20th, 2000
Patent Number: 7,214,371
This patent covers various matrices that are seeded with cells in vitro and implanted in vivo into myocardial tissue so as to allow regeneration or healing. The patent uses a porous polysaccharide composition for shaping the matrics since it allows optimal cell viability and differentiation in vitro.
The patent also covers embedding of various growth factors and cytokines in the matrix so...
Inventors: Cohen; Smadar (Beer Sheva, IL), Dar; Ayelet (Rehovot, IL), Etzion; Sharon (Beer Shevea, IL), Perets; Anat (Bet-Shemesh, IL), Shaprut; Sigalit (Beer Sheva, IL), Leor; Jonathan (Gane' Tikva, IL)
Assignee: Ben-Gurion University of the Negev Research & Development Authority (Beer-Sheva, IL)
Date of First Priority Issue: Friday September 1st, 2000
Patent Number: 7,198,641
This patent covers scaffolds that are useful for hair replacement. Essentially the patent has claims around a scaffold that is made of:
- a bioabsorbable polymer
- hair follicle progenitor cells
The scaffold having the shape approximately to the shape of a hair follicle.
The assignee company, Aderans Research Institute, Inc., is extensively involved in both making wigs, as well as...
Inventors: Barrows; Thomas H. (Austell, GA)
Assignee: Aderans Research Institute, Inc. (Beverly Hills, CA)
Date of First Priority Issue: Tuesday August 8th, 2000
Patent Number: 6676675
This patent provides biocompatible surfaces which can be used for growing nerve cells on that are derived from stem cells. This type of technology will be critical for generation of neural networks in vitro and in vivo, and eventually for the ability to expand central nervous system function.
Inventors: Mallapragada, Surya K. (Ames, IA); Heath, Carole (Seattle, WA); Shanks, Howard (Ames, IA); Miller, Cheryl A. (Irvine, CA); Jeftinija, Srdija (Ames, IA)
Assignee: Iowa State University Research Foundation, Inc. (Ames, IA)
Date of First Priority Issue: Wednesday April 19th, 2000
Patent Number: 6960427
At face value this patent seems to be extremely broad. The issued claims, which have one independent claim, cover pretty much any type of vascularized bioengineered tissue. The claim is not restricted to type of tissue or method of generating the tissue. It covers the introduction of at least one blood vessel into either a tissue or a matrix which has cells in it, growing of the tissue in...
Inventors: Haverich, Axel (Isernhagen, DE); Kofidis, Theo (Hannover, DE)
Assignee: Artiss GmbH (Hannover, DE)
Date of First Priority Issue: Monday April 3rd, 2000
Patent Number: 7,229,826
This patent covers a method of identifying genes associated with generation of bone tissue. The one issued claim covers the growth of a bone progenitor cell in media containing one or more members of the TGF family, and then assessing gene expression modification as the bone progenitor cells are differentiating into bone.
Inventors: Kale; Sujata (Boston, MA), Long; Michael W. (Northville, MI)
Assignee: The Regents of the University of Michigan (Ann Arbor, MI)
Date of First Priority Issue: Tuesday December 28th, 1999