News Posts
Forcing Differentiation
Durham, NC - Classically hematopoietic stem cells were known to differentiate into myeloid (monocyte and granulocyte) and lymphoid (T cell, B cell, NK cell) lineages. More recent studies have demonstrated differentiation into cardiomyocytes, neurons, and other tissue cells. The signals associated with hematopoietic stem cell differentiation into myeloid and lymphoid cells are currently...Friday June 1st, 2007 @ 03:42:40 EST
Treating Heart Failure With Bone Marrow Stem Cells
[Watch the Video]Sunday May 27th, 2007 @ 18:40:35 EST
Calling All Stem Cells !!!
Minneapolis, Minnesota - It is known that subsequent to cardiac infarction, various cytokines are produced by the injured myocardium that mobilize endogenous stem cells from the bone marrow into systemic circulation, and specifically "calling" them to home to the ischemic tissue. Unfortunately, this process occurs only to a small extent and full repair of the myocardium after injury seldom...Friday May 25th, 2007 @ 20:40:39 EST
Autoimmunity by non-Th1 cells
Minneapolis, MN - Old school immunology divided responses into Th1 (inflammatory, intracellular responses) and Th2 (antibody mediated, extracellular responses). Classical autoimmune diseases such as Type 1 Diabetes, multiple sclerosis, and rheumatoid arthritis were considered primarily Th1 type diseases. More recently, the "dogma" of Th1/Th2 immunity has been subjected to numerous critism...Wednesday May 23rd, 2007 @ 02:19:07 EST
Embryoid Bodies as Models of Embryogenesis
Philadelphia, Pennsylvania - Cellular positioning during embryogenesis is a complex process involving numerous soluble and cell surface bound factors. A recent paper (Rula et al. Cell autonomous sorting and surface positioning in the formation of primitive endoderm in embryoid bodies. Genesis. 2007 May 15;45(6):327-338) using artificially generated embryoid bodies to further investigate this...Thursday May 17th, 2007 @ 21:42:14 EST
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hTERT GFP for stem cell detection
Kyoto, Japan – The concept of each tissue containing resident stem cells is not new. For example, it is known that in the liver, hepatic epithelial cells expressing common markers for hepatic and stem cells such as CD90, CD44 and CD29 act as precursors, capable of generating new hepatic tissue following injury (Khuu et al. Epithelial cells with hepatobiliary phenotype: is it another stem...Thursday May 17th, 2007 @ 21:36:27 EST
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Embryonic Stem Cell for Tympanic Healing
Stockholm, Sweden - Otitis media (ear infection) occurs in many young children and sometimes results in perforation of the tympanic membrane. Although surgical treatments are available for perforated membranes, these are quite painful. In a recent study embryonic stem cells were used to accelerate healing of experimentally damaged tympanic membranes (Rahman et al. Healing time, long-term...Tuesday May 15th, 2007 @ 12:10:22 EST
Embryonic-like stem cells in marrow
Louisville, Kentucky - The presence of embryonic-like stem cells has been reported in cord blood as well as amiotic fluid. In a recent review (Kucia et al. Bone marrow-derived very small embryonic-like stem cells: Their developmental origin and biological significance. Dev...Tuesday May 15th, 2007 @ 10:56:00 EST
PGI2 Regulates Myogenesis
Atlanta, USA - Muscle satellite cells are located beneath the myofiber basal laminae (under the basement membrane surrounding each myofiber) and close to capillaries. They play a critical role in repair and turn over of muscle, acting as a supply of progenitor cells. In a recent paper (Bondesen et al. Inhibition of myoblast migration by prostacyclin is associated with enhanced cell...Monday May 14th, 2007 @ 22:27:10 EST
Olfactory Ensheathing Cells R Different Than Schwann Cells
Kingston, Canada - Olfactory ensheathing cells are a type of glial cell specific to the olfactory system. The primary purpose of the olfactory ensheathing cells is to induce remyelination of damaged nerves, as well as to allow for regeneration in specific circumstances. Numerous groups have used olfactory ensheathing cells for acceleration of spinal cord injury. For example, Dr...Monday May 14th, 2007 @ 18:34:25 EST