News Posts
Mesenchymal Stem Cells for Spinal Cord Injury
Seoul, Korea - Mesenchymal stem cells are utilized primarily for treatment of inflammatory conditions, for example the 2 clinical trials by Osiris therapeutics that are currently in Phase III are both treating graft versus host disease and Crohn's Disease...inflammatory conditions. The potent ability of mesenchymal stem cells to assist in tissue healing through induction of endogenous...Monday April 30th, 2007 @ 15:33:13 EST
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Stem Cells for Erectile Dysfunction
Seoul, Korea - Despite introduction of phosphodiesterase V inhibitors such as Viagra for the treatment of erectile dysfunction, many patients remain unresponsive due to underlying endothelial and/or smooth muscle abnormalities in the corpus cavernosum and vessels supplying it. Mesenchymal stem cells offer the possibility of treatment for erecticle dysfunction due to their ability to...Friday April 27th, 2007 @ 12:08:11 EST
Lasers and Stem Cells
Tel-Aviv, Israel - The use of low level laser irradiation to promote healing has been documented clinically (Lagan et al. Low-intensity laser therapy/combined phototherapy in the management of chronic venous ulceration: a placebo-controlled study. J Clin Laser Med Surg. 2002 Jun;20(3):109-16). Since some authors believe that low level laser irradiation possesses mitogenic effects for various...Thursday April 26th, 2007 @ 17:17:28 EST
ES to Islet
Seoul, Korea - A recent study (Shim et al. Directed differentiation of human embryonic stem cells towards a pancreatic cell fate. Diabetologia. 2007 Apr 23) reported generation of functional islet-like cells from human ES cells through the following steps: 1. ES cells placed in suspension culture to promote embryoid body formation 2. Culture in serum 3. Add activin 4. Add retinoic...Thursday April 26th, 2007 @ 10:06:48 EST
Mesenchymal Gene Therapy
Busan, Korea - The period of pancytopenia after hematopoietic stem cell transplantation is a significant cause of morbidity and mortality. Accordingly, growth factors, such as G-CSF have been developed clinically to reduce the period of neutropenia so as to minimize the risk of infection during the immunosuppressed state. Since mesenchymal stem cells are known to secrete numerous...Wednesday April 25th, 2007 @ 17:01:37 EST
Who Say's Brain Cells Dont Multiply
Trieste, Italy - Although in recent years numerous reports of neural plasticity have been made, little clinical evidence of this has been demonstrated in consistent systems that are highly reproducible. In a recent paper (Sgubin et al. Activation of endogenous neural stem cells in the adult human brain following subarachnoid hemorrhage J Neurosci Res. 2007 Apr 23) a very interesting system...Wednesday April 25th, 2007 @ 16:47:25 EST
Importance of Injury in Stem Cell Neurorepair
Milano, Italy - In various pathological conditions injured tissue attracts endogenous stem cells through release of various factors. This is known, for example, in the area of myocardial infarction where circulating levels of stem cells increase in the peripheral blood of patients after heart attacks. Theoretically, the idea is that the ischemia and tissue damage release systemic factors...Thursday April 19th, 2007 @ 09:28:35 EST
In vitro ALS model
Cambridge, Massachusetts - Generation of in vitro models of human diseases allows utilization of high-throughput screening, as well as isolated molecular dissection of events in order to identify targets for intervention. A recent paper (Di Giorgio et al. Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model Nat Neurosci. 2007 Apr 15) developed an in...Wednesday April 18th, 2007 @ 03:47:42 EST
Sweet BM: Glucose changing BM to pancreatic like cells
[Watch the Video] US Patent 7,169,608Tuesday April 17th, 2007 @ 02:59:52 EST
CD55 as a marker of Cancer Stem Cells
Osaka, Japan - The search for tumor stem cells has revealed numerous markers that are present on non-tumor stem cells as markers of tumor stem cells. For example, the recent discovery that CD133 is found on colon cancer stem cells should not be a surprise, since this marker is also found on other types of stem cells. What SHOULD BE A SURPRISE is the recent publication...Tuesday April 17th, 2007 @ 01:30:32 EST