News Posts
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Sunday April 15th, 2007 @ 16:04:29 EST
Durham, NC –
As stem cell therapeutics progress towards becoming a clinical reality, it is becoming more and more apparent that not only is it important to administer the proper type of stem cells, but also to ensure that a proper environment surrounds them, so that they may differentiate into the needed tissue.
In a recent paper (Yim et al. Synthetic nanostructures inducing...
Sunday April 15th, 2007 @ 16:02:46 EST
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Sunday April 15th, 2007 @ 14:39:44 EST
Beijing, China -
Treatment of diabetes by stem cell derived beta calls is an attractive prospect. Jiang et al (In vitro derivation of functional insulin-producing cells from human embryonic stem cells. Cell Res. 2007 Apr 10) recently reported a serum free method of inducing ES cells to differentiate into cells capable of producing insulin in vitro and in vivo.
The investigators treated...
Thursday April 12th, 2007 @ 11:18:55 EST
Singapore -
The ability to generate new endothelial cells would allow for treatment of a wide variety of diseases in which ischemia acts as a culprit. Use of stem cells, as well a growth factors for stimulation of new blood vessel production, a process called angiogenesis has been a topic of intense research and clinical investigation.
In a recent paper (Rufaihah et al. Directing...
Thursday April 12th, 2007 @ 01:56:04 EST
Milan, Italy -
Stem cells are currently being considered for numerous conditions afflicting humanity. Stem cell therapy of cancer is very interesting since it offers two possibilities: The first to use the stem cells as a "trojan horse" to carry a toxic payload to the tumor; and the second, to use the stem cell to produce factors that would induce the tumor to differentiate so as to lose its...
Friday April 6th, 2007 @ 16:20:34 EST
Naples, Italy -
Since the majority of chronic human diseases are associated with multifactorial causes and multifactorial mechanisms, the ability of a monotherapeutic intervention to evoke long term benefit seems, at least theoretically, not realistic. The field of therapeutic angiogenesis has often been critized for the utilization of only single angiogeneic approaches clinically, while in...
Friday April 6th, 2007 @ 16:08:55 EST
Chiba, Japan -
The clinical use of G-CSF (Neupogen) has allowed for mobilization of stem cells in the peripheral blood stem cell transplant setting, as well as a means of accelerating hematopoietic recovery in a variety of settings.
A recent paper suggests that mobilization of stem cells using G-CSF may be useful not only for hematopoietic indications but also for inducing repair post spinal...
Tuesday April 3rd, 2007 @ 16:22:39 EST
Munich, Germany -
It is known that when bone marrow stem cells are injected intravenously into a recipient, the injected cells home to the recipient bone marrow because the bone marrow stroma secretes various chemoattractant factors that cause migration of cells. Along these lines, induction of tissue injury is also known to cause chemoattraction of bone marrow stem cells to the area of...
Monday April 2nd, 2007 @ 11:29:46 EST
Genoa, Italy -
The ability of
mesenchymal stem cells to suppress immune response is well known. However, the mechanisms associated with such immune suppression are still being elucidated. While it is known that mesenchymal stem cells are clinically effective at inhibiting graft versus host disease, the mechanism of this activity may...
Monday April 2nd, 2007 @ 00:31:40 EST