News Posts
Clinical Trial of CD34 Stem Cells for Liver Failure
London, UK-The use of stem cells to treat liver failure is not new. Animal models, as well as pilot clinical trials have demonstrated statistically significant improvement in liver enzyme values and overall clinical scores. In a recent study (Pai et al. Autologous Infusion of Expanded Mobilized Adult Bone Marrow-Derived CD34+ Cells Into...Sunday July 20th, 2008 @ 15:05:23 EST
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Interferon gamma as a "danger signal"
Boston, MA -Although stem cell therapy has demonstrated some benefit in a variety of cardiac conditions, heart transplantation is still the only option for many patients with end-stage heart failure. The problem with heart transplantation is that firstly there are not enough donors, and secondly, the patients have to take immune suppressive drugs for...Sunday July 13th, 2008 @ 17:01:10 EST
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Liquid tumors need blood
It is a widely accepted principle that angiogenesis is required for new tissue growth. This is particularly true in cancer where numerous therapeutic approaches have been used to target tumor angiogenesis, thus effectively choking the tumor. An interesting take on blocking angiogesis is that the endothelial cells, which are responsible for angiogenesis do...Wednesday July 9th, 2008 @ 19:20:29 EST
4-1BB inhibits myelopoiesis/dendritic cell generation
San Diego, CA -We at StemCellPatents.com are very interested in trans-disciplinary findings (scientific disciplines are made by humans to make learning easier but the body functions by integration). One area where scientific disciplines are beginning to overlap more and more is between stem cells and the immune system. We all know that some types of stem cells, such asStem Cell Therapy of Multiple Sclerosis: Positive Case Reports
[Watch the Video] The use of stem cell therapy for multiple sclerosis has been previously reported in case reports, including from Dr. Simon Slavin's group in Israel. In multiple sclerosis the rationale for why stem cell therapy would have beneficial effects derives from observations that some types of stem cells, such asLeukemia Vaccine
Houston, Texas -Immune responses against tumors have been known for more than 100 years. For example Dr. Coley of Sloan Kettering observed that various bacterial infections induced regression of tumors in cancer patients. One particular type of cancer that has been demonstrated to respond to immunotherapy is chronic myeloid leukemia, a cancer of the...Wednesday July 2nd, 2008 @ 10:40:05 EST
Go Cytori Go !
Tokyo, Japan -One of the issues of adult stem cell therapy is processing. When using allogeneic cells, for example, Endometrial Regenerative Cells, the cells can be made at a dedicated facility and shipped to where needed. On the other hand, autologous cells present a little more difficulty since: a) people don't like having holes drilled in their bones...Thursday June 26th, 2008 @ 02:15:55 EST
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HGF-1 Double Blind Trial for Critical Limb Ischemia
Durham, NC -Stimulation of angiogenesis has previously been demonstrated using various cell therapy methods, such as administration of autologous bone marrow stem cells either in the heart or ischemic leg muscle. Autologous approaches sometimes are difficult since on the one hand they require cellular processing, which may not be...Monday June 23rd, 2008 @ 14:22:19 EST
Clinical Evidence of Glioma Stem Cell
Lausanne, Switzerland -The concept of a cancer stem cell, or "seed cell" that replenishes and sustains the tumor mass is gaining more and more momentum in scientific and corporate circles. An example, of course, is the Oncomed-GSK deal that is estimated to be worth approximately 1.5 billion dollars, despite Oncomed being only in preclinical...Sunday June 22nd, 2008 @ 17:11:29 EST
4.1BB Induces CD34 To Monocyte Differentiation
Singapore - There are numerous examples of molecules associated with immune response having regulatory effects on stem cell function, and vice versa. Immune control of hematopoiesis can be seen in an issued US patent (# 7,332,158) describing that administration of activated peripheral blood mononuclear cells accelerates...Saturday June 21st, 2008 @ 14:00:16 EST