News Posts
Mesenchymal stem cells made into nucleus pulposus cells
Lumbar disc degeneration is a significant cause of morbidity. Given that the key cells maintaining the mass of the disc are nucleus pulposus cells, one of the aims in regenerative medicine has been to treat disc degeneration by administration of stem cells. However, one major question arises, would it be more beneficial to administer stem cells into...Friday May 16th, 2008 @ 20:00:18 EST
Immunology Instead of Stem Cells: Vaccine for Alzheimer's
Huntington Beach, CA -A recent paper from Dr. Agadjanyan's group at the Institute of Molecular Medicine (Movsesyan et al. Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy. PLoS ONE 2008 May 7;3(5):e2124) reports the successful treatment of a mouse model of Alzheimer's using DNA vaccination against amyloid protein...Sunday May 11th, 2008 @ 17:30:29 EST
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Interview with Novocell CEO Alan Lewis
[Watch the Video]In this StemCellPatents.com interview, our special guest interviewer, Thomas Ichim, CEO of Medistem, speaks with Alan Lewis, CEO of Novocell, regarding the company's advances towards curing diabetes. This interview examines many aspects of Novocell which...Tuesday April 29th, 2008 @ 23:38:49 EST
FGF-1 Gene Therapy Double Blind Trial
Münster, Germany -Understanding and manipulating the formation of new blood vessels, a process called angiogenesis, has been one of the highly sought-after goals of the biotechnology industry. One the one hand, inhibition of angiogenesis is desirable in cancer, since tumors need new blood vessels to stay alive. On the other hand, angiogenesis stimulation could be a...Wednesday April 23rd, 2008 @ 19:50:50 EST
Parathyroid hormone mobilization and limb ischemia
Naples, Italy -The administration of bone marrow stem cells into ischemic muscles for treatment of critical limb ischemia is currently being performed in clinical trials, with results demonstrating stimulation of angiogenesis and functional improvement. Given that a substantial amount of the angiogenic response seems to be...Wednesday April 23rd, 2008 @ 11:30:14 EST
Menstrual Blood Stem Cells Part 2
Tokyo, Japan -It was previously reported by the company Medistem (mdsm.ob) that a population of multipotent stem cells exist in menstrual blood. These cells, which Medistem termed "endometrial regenerative cells" appear to possess some of the properties of mesenchymal stem cells, such as expression of CD90 and CD105, as well...Tuesday April 22nd, 2008 @ 03:38:18 EST
Expanding Hematopoietic Stem Cells by Removing Inhibitors
The desire to expand hematopoietic stem cells is not only a basic research accomplishment but would allow for widespread use of autologous stem cells, as well as expand the utilization of cord blood stem cells which are usually of concern due to the relatively low stem cell content.Various methods of expanding hematopoietic stem cells exist, for example, treatment with...Sunday April 20th, 2008 @ 15:22:22 EST
"I need blood" says the embryoid body
Tokyo, Japan -Embryonic stem cells have a very high potential to generate various tissues, a potential so high that it actually serves as a drawback in some senses. See, embryonic stem cells, when grown in floating cultures form embryoid bodies, and in these embryoid bodies the embryonic stem cell starts differentiating into a wide variety of...Sunday April 13th, 2008 @ 15:39:22 EST
Stem Cell Cytokines Preventing Ischemia Reperfusion
Osaka, Japan -Granulocyte colony stimulating factor (G-CSF) is one of the largest selling products of the biotechnology industry. Approved uses of this recombinant cytokine include stimulation of neutrophil production after chemotherapy or bone marrow transplantation. Another use is in mobilizing the hematopoietic stem cells to leave the...Saturday April 12th, 2008 @ 21:32:30 EST
Treating back pain with mesenchymal stem cells
Pittsburgh, Pennsylvania -Vertebral disc degeneration is a major cause of suffering internationally. Although various interventions exist, such as disc replacement and surgical fusion, these have numerous long-term limitations such as need for resurgery, degeneration of the adjacent disc, and relapse of pain. One exciting method of treating disc...Saturday April 12th, 2008 @ 14:52:30 EST
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