News Posts
Stroke without thrombolytics calls stem cells
Regensburg, Germany -Bone marrow stem cells are known to possess numerous regenerative properties in humans (clinical trials), including healing of heart attack damaged myocardium, reversing liver failure, and stimulating new blood vessel production in patients with ischemic limbs. Bone marrow stem cells...Monday June 16th, 2008 @ 02:33:35 EST
Mesenchymal Stem Cells for Multiple Sclerosis
Jerusalem, Israel -Stem cell therapy for conditions such as multiple sclerosis is promising in part because of the possibility of remyelination, as well as the immune modulatory properties of the stem cells, especially mesenchymal stem cells. While others have published that mesenchymal...Thursday June 12th, 2008 @ 03:30:25 EST
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5 Comments
Notch Ligand Inhibits Angiogenesis
Oxford, UK -The notch signalling pathway has been widely studied in development and tissue specification. Notch acts as a receptor for various ligands and upon binding translocates into the nucleus to induce expression of various genes. Two ligands of notch, Delta and Serrate have been implicated in the inhibition of stem cell differentiation. ...Thursday June 12th, 2008 @ 02:43:00 EST
T regulatory cells that inhibit multiple sclerosis that are not T reg
Cambridge, MA -Multiple sclerosis is mediated by autoimmune T cell responses against components of the myelin basic sheath, for example myelin basic protein, myelin oligodendrocyte protein, and phospholipid protein. Stem cell therapy, especially with universal donor mesenchymal stem cells or endometrial regenerative cells, has...Wednesday June 4th, 2008 @ 11:00:21 EST
Temporary Hypoxia is Good for Mesenchymal Stem Cells
St Louis, MO -Mesenchymal stem cells are very exciting since they can be used in an allogeneic manner. While these cells have demonstrated therapeutic effects in liver failure, heart failure, and even diabetes, the main question still remains, how to increase their...Tuesday June 3rd, 2008 @ 10:28:52 EST
Multiple Sclerosis T Cell Receptor Diversity
[Watch the Video]At StemCellPatents.com we have discussed both in vitro and in vivo evidence for stem cells being able to play a therapeutic effect on multiple sclerosis. The main mechanism by which this occurs is through the ability of stem cells to generate new myelin, and in some cases actually regenerate neurons. However, in multiple sclerosis the main cause of the disease is...Monday June 2nd, 2008 @ 08:55:45 EST
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1 Comment
Mesenchymal Stem Cells Augmented by Estrogen
Indianapolis, Indiana - Mesenchymal stem cells, have very potent therapeutic potential because they can be used in an allogeneic manner, they can differentiate into many new types of tissue, and they produce numerous growth factors. Mesenchymal stem cells have been demonstrated in non-clinical systems to be effect inDuchenne Muscular Dystrophy Calls Stem Cells
Milan, Italy -Duchenne Muscular Dystrophy is a lethal genetic condition, characterized by progressive muscle weakness caused by mutations in the dystrophin gene. Approaches to treatment of this condition have included the use of cord blood stem cells, however little functional improvement is seen, even in animal models. US patent 2 Comments
Mesenchymal Stem Cells Reverse Diabetes in C57 Strep Model
Santiago, Chile -A recent paper (Ezquer et al. Systemic administration of multipotent mesenchymal stromal cells reverts hyperglycemia and prevents nephropathy in type 1 diabetic mice. Biol Blood Marrow Transplant 008 Jun;14(6):631-40) described the therapeutic impact of bone marrow derived mesenchymal stem cells administered to mice with experimental diabetes.Streptozotocin is an antibiotic...Wednesday May 21st, 2008 @ 11:06:10 EST
Stem Cells and Liver Failure
Shanghai, China -Liver failure is a major cause of moribidity and mortality, cited by some as the 7-10th largest cause of death. The possibility of stem cell therapy for liver failure is particularly attractive since intravenous administration of cells usually results in deposition into the liver. Animal studies have demonstrated that endogenous hepatic stem...Sunday May 18th, 2008 @ 16:29:56 EST