Class: Type (195)
Lineage restricted glial precursors from the central nervous system
Patent Number: 6900054Glial cells performed numerous functions in the nervous system including providing support, nutrition, and form myelin for neurons. They represent 90% of the cells in the central nervous system. The ability to generate glial cells ex vivo is critical not only for the potential of administering such cells to damaged areas, but also for using these cells are vectors to carry genes in order to...
Human bone accessory cells
Patent Number: 6576465This patent covers a type of stem cell, or actually a cell that helps bone generating stem cells to perform their function. Therapeutic applications of this cell range from in vitro expansion of bone stem cells, to in vivo induction of bone regeneration.
Human embryonic stem cells having genetic modifications
Patent Number: 7,413,904This patent covers a method of generating human embryonic stem cells that are genetically modified. Specifically, it claims the methodology of: obtaining a human embryonic stem cells that are in absence of feeder cells but kept viable in an extracellular matrix composition with media conditioned by fibroblasts, inserting into the cells a polynucleotide, and maintaining the cells in an...
Human CNS neural stem cells
Patent Number: 5968829This patent provides a type of neural stem cells, including stem cells derived from the basal forebrain. Disclosed are methods of maintaining the neural stem cells in culture, as well as ways of differentiating them into neurons.
Mammalian common lymphoid progenitor cell
Patent Number: 6908763The stem cell identified in this patent is a type of progenitor cell that can differentiate only along the lymphoid, but not myeloid lineage. These cells are useful for situations in which lymphopoiesis is desired, for example, after lymphodepletion of a cancer patient in protocols used for homeostatic induced antitumor immunity. The patent essentially covers a cell type that expresses...
Mammalian common lymphoid progenitor cell
Patent Number: 7,297,329This patent covers "transplantation of lymphopoietic activity" into a mammal by the transfer of cells possessing "common lymphoid progenitor" activity. Essentially the claims state that this "common lymphoid progenitor" activity correlates with cells that are express low levels of c-kit, high levels of the alpha receptor for interleukin-7 and are lineage negative. This makes sense that it...
Neuroepithelial stem cells and glial-restricted intermediate precursors
Patent Number: 7037720This patent appears to cover a progenitor cell of neuronal lineage. Specifically the patent has 2 independent claims. The first covers a population of neuroepithelial stem cells derived from embryonic sources which are dependent of FGF for proliferation and can differentiate into CNS neuronal cells and CNS glial...
Lineage-restricted neuronal precursors and methods of isolation
Patent Number: 6787353This patent teaches ways of generating a new type of neuronal precursor cell from embryonic tissue. The cells are negative for the marker A2B5 and positive for expression of NCAM.
Isolation of lineage-restricted neuronal precursors
Patent Number: 6734015This patent covers a type of neuronal stem cell that is restricted in its differentiation ability to the neuronal, but not astrocyte or glial lineage. The patent covers a cell that is E-NCAM positive, FGF-dependent, and derived from embryonic sources.
Human mesenchymal stem cells from peripheral blood
Patent Number: 6261549In the same way that hematopoietic stem cells can be purified from peripheral blood, and in the same way that they can be mobilized, this patent teaches that the concept is also applicable to mesenchymal stem cells.