Class: Type (195)
Primate embryonic stem cells
Patent Number: 5843780This is one of the composition of matter patents on embryonic stem cells. It belongs to what is called the "WARF Patents" covering the use and production of human and primate embryonic stem cells.
Embryonal cardiac muscle cells, their preparation and their use
Patent Number: 5928943This patent covers specific embryonically-derived cells that have stem cell ability to regenerate myocardium after injury. Methods for selecting cells with such potential are disclosed.
Porcine neural cells and their use in treatment of neurological deficits due to neurodegenerative diseases
Patent Number: 6258353This patent covers the use of a specialized cell population obtained from xenogeneic sources for the stimulation of recovery of various neurological disorders. Specifically, the patent covers pig lateral ganglionic eminence cells that are treated so as to not elicit immune rejection.
Isolated and modified porcine cerebral cortical cells
Patent Number: 6140116This patent covers a type of stem cell, specifically xenogeneic pig cerebral cortical cells. These cells, when treated so as to not elicit immune rejection, are useful for the treatment of various neurodegenerative disorders.
Bone precursor cells: compositions and methods
Patent Number: 6740493This patent teaches how to diagnose, or to predict a bone disease through identifying the bone stem cell content and activity of the patient.
Human marrow stromal cell lines which sustain hematopoiesis
Patent Number: 6103522Culture of early hematopoietic stem cells (human ones) was previously performed on murine stromal cells, and stromal cells of mouse that are transfected with certain genes. In this patent a human stromal cell line is provided (can be bought at ATCC), which is capable of sustaining expansion of early human hematopoietic stem cells. This cell line allows for growth and...
Human marrow stromal cell lines which sustain hematopoieses
Patent Number: 5879940This patent covers a "stromal" cell line that supports hematopoiesis in vitro. I wonder how different are these "stromal" cell lines from the mesenchymal stem cells that are described by Osiris?
Reversal of insulin-dependent diabetes by islet-producing stem cells, islet progenitor cells and islet-like structures
Patent Number: 6703017This patent covers the treatment of diabetes using islets and/or islet-like cells that are generated from stem cells residing in the pancreatic duct.
Transduced mesenchymal stem cells
Patent Number: 5591625This patent covers mesenchymal stem cells that are transfected with anything. Mesenchymal stem cells are very useful for clinical development since that do not need to be matched with HLA of the recipient in many situations, thus allowing for the use of an "off the shelf" product. The advantage of transfecting mesenchymal stem cells with genes is that the...
Embryonic stem cells capable of differentiating into desired cell lines
Patent Number: 6432711This patent covers the generation of neurons and muscle cells from embryonic stem cells. The patent uses fetal calf serum which can be a drawback to clinical implimentation.