Class: Type (195)

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Genetic modification of primate hemopoietic repopulating stem cells

Patent Number: 6312957

Hematopoietic stem cells are an ideal vector for gene therapy since they repopulate the whole body, and in some cases can differentiate into various tissues in the body. This patent teaches the use of adeno-associated virus vectors to transfect hematopoietic stem cells so that the hematopoietic stem cells can repopulate the host and deliver the protein product of the gene to where it is...

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Mammalian cells that have increased proliferative capacity

Patent Number: 7,195,911

This patent covers the expansion of telomeres in a wide variety of human cells using the telomerase reverse transcriptase. This patent belongs to a family of earlier Geron patents covering the overcoming of telomere shortening through induction of "telomerase" activity into cells. The IP field of telomerase is pretty crowded and this patent has to be read carefully by those interested in...

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Retinal stem cells

Patent Number: 6117675

This patent covers retinal stem cells. These stem cells are useful for the treatment of a variety of ocular disorders including viral retinitis, blind spots, or loss of color vision.

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Human CNS cell lines and methods of use therefor

Patent Number: 6713247

This patent covers neuronal cell and neuronal stem cell lines that are conditionally immortal. These may be used for therapeutic purposes, and also for in vitro drug discovery.

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Unactivated oocytes as cytoplast recipients for nonprimate mammalian and pig nuclear transfer

Patent Number: 7,432,415

This is one of Ian Wilmut's many patents on cloning animals (for example 7,321,076, 7,304,204, 6,525,243) 

This one covers essentially a method of preparing a nonprimate mammalian embryo capable of developing into a live-born nonprimate mammalian animal comprising:

(a...

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Multipotent neural stem cells from peripheral tissues and uses thereof

Patent Number: 6787355

This patent covers multipotent stem cells that are generated from skin or from tongue tissue. This stem cell type is particularly useful for generation of neural stem cells and neurons.

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Embryonic stem cell lines obtained from C3H/HeN and DBA/1J mouse strains

Patent Number: 5985659

This patent provides some embryonic stem cell lines derived from mice that are useful for the creation of knockout animals.

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Human hematopoietic stem and progenitor cell antigen

Patent Number: 6455678

This patent appears to cover the stem cell antigen AC133, otherwise known as CD133. This antigen is found not only on hematopoietic stem cells, but also on stem cells capable of inducing angiogenesis. This patent may be useful for people who do not want to licence CD34.

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Cultured inner cell mass cell lines derived from bovine or porcine embryos

Patent Number: 5905042

This patent provides technologies for growing stem cells that are useful for the generation of chimeric cows or pigs.

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Mouse embryonic stem cell lines

Patent Number: 6190910

This patent teaches the generation of several embryonic stem cell lines that are useful for creation of knockout mouse models.

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