Class: Type (195)
Human adult astrocytes, their preparation and uses thereof
Patent Number: 6943016This invention teaches how to obtain a population of astrocytes that is free of microglial cells from a fresh biopsy specimen. The invention has one independent claim covering the process of explanting a tissue that contains both astrocytes and microglial cells, culturing the cells in vitro under conditions that selectively promote adherence of the astrocytes to the culture vessel, and after...
Adipose-derived stem cells and lattices
Patent Number: 7,470,537The therapeutic benefits of adipose derived stem cells have been demonstrated in animal trials and are currently undergoing several clinical trials. Although patents have been issued on methods of isolating fat derived stem cells, such as 7,390,484 held by Cytori, or 7,078,232 held by Artecel covering adipose stem cells...
Adipose-derived stem cells and lattices
Patent Number: 6777231This is one of the founding patents covering work performed by Cytori, formerly Macropore. The patent covers an adipose derived stem cell that can diffentiate into bone, cartilage cell, nerve, or muscle cells.
Compositions of enriched central nervous system stem cell and progenitor cell populations
Patent Number: 7,153,686This patent covers a "Neurosphere Initiating Cell" isolated by its expression of the marker CD133. CD133 is expressed in a variety of stem cells and was recently shown to be found on cancer stem cells as well. Essentially, neurospheres are aggregates of neural cells that are grown in tissue culture...
Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations
Patent Number: 7,217,565This patent covers the isolation of neural stem cells, primarily from human fetal origin. These stem cells are purified by 2 steps. First the fetal cells are bound to the antibody 8G1 and then they are further purified for expression of AC133 and 5E12.
This patent is similar to several others from the same family such as
Double nuclear transfer method and results thereof
Patent Number: 7,531,715The area of cloning is of great interest in terms of therapeutics development, not only from the perspective of generating de novo stem cell populations, but also the possibility of making transgenic animals for practical purposes such as food or protein production. Accordingly, numerous patents have been issued on all sorts of variations of the cloning process, as well as...
Transgenic circulating endothelial cells
Patent Number: 6852537This patent covers the expansion of endothelial cells by growing on collagen-1 coated plates in the combination of various growth factors such as FGF, VEGF, and IGF. Additionally, numerous culture conditions for endothelial expansion are disclosed. The abstract of the patent discribes the use of endothelial cells for gene therapy, but...
Embryonic stem cells
Patent Number: 6875607Despite its appealing title, the claims of this patent appear only to cover the alteration of differentiation of embryonic stem cells, in part through providing the use of feeder cell layers.
Myeloid precursor cell useful for gene therapy and for modulation of immune responses
Patent Number: 7,198,909Myeloid progenitor cells are known to be responsible for producing polymorphonuclear leukocytes as well as monocytes in the blood. Besides their well-known function in the classical hematopoietic system, myeloid progenitor cells ahve been reported by various groups to have immune modulatory function, specifically, the ability to inhibit immune responses through factors such as
Trophoblast cell preparations
Patent Number: 6630349This patent provides trophoblast cell lines that are of murine origin. Since the trophoblast is similar to cancer cells in terms of immune suppression and metastizing ability, this patent is useful for the generation of a xenogeneic cancer vaccine, similar to XenoVax. The fact that trophoblast stem cells are provided is useful since this can be a good off the shelf starting population for...