Class: Type (195)
Patent Number: 6429012
This is a patent for a cell population that can differentiate into both the hematopoietic lineage and the endothelial lineage.
Inventors: Kraus, Morey (Worcester, MA); Wilder, Paul (Worcester, MA)
Assignee: Viacell, Inc. (Worcester, MA)
Date of First Priority Issue: Tuesday June 10th, 1997
Patent Number: 6830927
This patent teaches how to generate neuronal stem cells that are bipotent into differentiating into central nervous system neurons as well as peripheral nervous system neurons. The patent uses neuronal stem cells that are extracted from specific parts of the embryo and cultured in fibroblast growth factor and chicken embryo extract.
Besides the intrinsic value of composition of matter on...
Inventors: Rao, Mahendra S. (Salt Lake City, UT); Mujtaba, Tahmina (Sandy, UT)
Assignee: University of Utah Research Foundation (Salt Lake City, UT
Date of First Priority Issue: Wednesday May 7th, 1997
Patent Number: 6361996
This patent provides a type of neural stem cell that is capable of differentiating into neural cells and glial cells. Specific properties of the stem cell are covered such as dependence on FGF.
Inventors: Rao, Mahendra S. (Salt Lake City, UT); Mayer-Proschel, Margot (Sandy, UT)
Assignee: University of Utah Research Foundation (Salt Lake City, UT)
Date of First Priority Issue: Wednesday May 7th, 1997
Patent Number: 6331406
This patent provides a new type of cell that can function as a stem cell, or is useful in the generation of stem cells. The cell population is characterized and is isolated from embryonic gonadal ridges.
Inventors: Gearhart, John D. (Baltimore, MD); Shamblott, Michael Joseph (Baltimore, MD)
Assignee: The John Hopkins University School of Medicine (Baltimore, MD)
Date of First Priority Issue: Monday March 31st, 1997
Patent Number: 6090622
This patent teaches a new type of stem cell that is isolated from the gonadal ridge.
Inventors: Gearhart, John D. (Baltimore, MD); Shamblott, Michael Joseph (Baltimore, MD)
Assignee: The Johns Hopkins School of Medicine (Baltimore, MD)
Date of First Priority Issue: Monday March 31st, 1997
Patent Number: 6986887
This patent teaches how to make stem cells less immunogenic by modification of the human leukocyte antigen content. Specifically the patent has 2 independent claims. The first covers modification of HLA-B and HLA-C, whereas the second covers modification of HLA-DR. Essentially the generation of "universal...
Inventors: Lawman, Patricia (Chipley, FL); Lawman, Michael J. P. (Chipley, FL)
Assignee: Morphogenesis, Inc. (Oldsmar, FL)
Date of First Priority Issue: Tuesday March 25th, 1997
Patent Number: 6011197
This patent teaches methods of cloning cattle.
Inventors: Strelchenko, Nikolai S. (DeForest, WI); Betthauser, Jeffrey M. (Windsor, WI); Jurgella, Gail L. (Madison, WI); Pace, Marvin M. (DeForest, WI); Bishop, Michael D. (Rio, WI)
Assignee: Infigen, Inc. (Deforest, WI)
Date of First Priority Issue: Thursday March 6th, 1997
Patent Number: 7,125,714
This patent covers a stem cell that expresses both CD34 and VEGFR-3. What is nice about this patent is that it covers cells with CD34 and VEGFR-3 from ANY source.
Inventors: Alitalo; Kari (Helsinki, FI), Joukov; Vladimir (Boston, MA)
Assignee: Licentia Ltd. (Helsinki, FI); Ludwig Institute for Cancer Research (New York, NY)
Date of First Priority Issue: Wednesday February 5th, 1997
Patent Number: 6235970
This patent teaches ways of generating stem cells, and inner cell mass cells through nuclear transfer. This patent is important for generation of embryonic stem cells, and offers the possibility of generation of autologous embryonic stem cells by nuclear transfer techniques.
Inventors: Stice, Steven L. (Belchertown, MA); Cibelli, Jose (Amherst, MA); Robl, James (Belchertown, MA); Golueke, Paul (Belchertown, MA); Ponce de Leon, F. Abel (Amherst, MA); Jerry, D. Joseph (Shutesbury, MA)
Assignee: University of Massachusetts, Amherst Campus (Amherst, MA)
Date of First Priority Issue: Friday January 10th, 1997
Patent Number: 6638763
This patent covers a specific type of early neuronal stem cell that is viable for a sigificant period of time after the host dies. These cells are transplantable and possess some properties of other neural stem cells, however in the patent, unique phenotypic and functional characteristics are provided.
Inventors: Steindler, Dennis A. (Memphis, TN); Laywell, Eric D. (Memphis, TN); Kukekou, Valery G. (Memphis, TN); Thomas, L. Brannon (Johnson City, TN)
Assignee: University of Tennessee Research Foundation
Date of First Priority Issue: Tuesday January 7th, 1997