Patents (1436 Stem Cell Patents)

Class: Type (195)

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Embryonic germ cells, method for making same, and using the cells to produce a chimeric porcine

Patent Number: 6194635

This patent teaches how to generate embryonic germ cells. These cells may be used for transgenic and knockout experiments, as well as for generation of stem cells with unique properties.

Inventors: Anderson, Gary B. (Davis, CA); Shim, Hosup (Davis, CA)
Assignee: The Regents of the University of California (Oakland, CA)
Date of First Priority Issue: Tuesday January 9th, 1996

Unactivated oocytes as cytoplast recipients of quiescent cell nuclei while maintaining correct ploidy

Patent Number: 6525243

This patent teaches ways of improving efficacy of cloning through nuclear transfer into oocytes that are in specific stages of proliferation. The use of cloning for generation of autologous embryonic stem cells offers incredible potential for regenerative medicine.

Inventors: Stockman Campbell, Keith Henry (Midlothian, GB); Wilmut, Ian (Midlothian, GB) Assignee: Roslin Institute (Edinburgh, GB)
Assignee: The Minister of Agricultural, Fisheries and Food (GB); Biotechnology & Biological Sciences Research Council (GB)
Date of First Priority Issue: Thursday August 31st, 1995

Unactivated oocytes as cytoplast recipients of quiescent and non-quiescent cell nuclei, while maintaining correct ploidy

Patent Number: 6252133

This patent covers a method of increasing efficacy of the cloning process. Cloning may be used as a source for the generation of stem cells of the embryonic type.

Inventors: Campbell, Keith Henry Stockman (Midlothian, GB); Wilmut, Ian (Midlothian, GB)
Assignee: Roslin Institute (Edinburgh) (Midlothian, GB); The Minister of Agriculture, Fisheries & Food (London, GB); Biotechnology & Biological Sciences Research Council (Swindon, GB)
Date of First Priority Issue: Thursday August 31st, 1995

Neuronal progenitor cells and uses thereof

Patent Number: 6251669

This patent covers a type of neural stem cell. In one embodiment the stem cells can be differentiated into gamma aminobutyric acid (GABA) expressing neurons.

Inventor: Luskin, Marla B. (Decatur, GA)
Assignee: Emory University (Atlanta, GA)
Date of First Priority Issue: Thursday July 6th, 1995

Neuronal progenitor cells and uses thereof

Patent Number: 5753505

This patent provides a new type of neural stem cell that can be used for screening or therapeutic purposes.

Inventor: Luskin, Marla B. (Decatur, GA)
Assignee: Emory University (Atlanta, GA)
Date of First Priority Issue: Thursday July 6th, 1995

Method of isolating bile duct progenitor cells

Patent Number: 5861313

This patent covers a type of stem cell that is isolated from the bile duct that can be induced to differentiate into various types of pancreatic cells including islets.

Inventors: Pang, Kevin K. (Belmont, MA); Homa, Monica W. (Marblehead, MA)
Assignee: Ontogeny, Inc. (Cambridge, MA)
Date of First Priority Issue: Wednesday June 7th, 1995

Human oligodendroglial progenitor cell line

Patent Number: 5830651

This patent covers a neural stem cell line that can differentiate into neurons, oligodendrocytes, and glial cells. This cell line can be used for drug discovery since it provides a uniform cellular population. These cells may be purchased by the public from ATCC.

Inventors: Cauley, Keith (Burlington, VT); Kukekov, Valery (San Diego, CA)
Assignee: Signal Pharmaceuticals, Inc. (San Diego, CA)
Date of First Priority Issue: Monday May 1st, 1995

Liver parenchymal cells having clonal growth ability, method for obtaining same, method for subculturing same, and subculturing system of primary hepatocytes

Patent Number: 6004810

This patent covers a type of liver stem cell that is useful for the treatment of various hepatic diseases. It will be interesting to compare this patent to the other ones in this directory that cover liver stem cells.

Inventors: Tateno, Chise (Hiroshima, JP); Yoshizato, Katsutoshi (Hiroshima, JP)
Assignee: Research Development Corporation of Japan (Saitama, JP)
Date of First Priority Issue: Tuesday April 11th, 1995

Method of preparing an undifferentiated cell

Patent Number: 7,410,773

This patent is either way ahead of its time, or there are some problems in its commercialization.  The patent covers a method of "dedifferentiating" mature cells in order to an immature phenotype or to increase the ability of the cells to act like stem cells. 

The first claim of the patent covers a means of augmenting the number of cells expressing a stem cell...

Inventors: Abuljadayel; Ilham Saleh (London, GB)
Assignee: Ghazi Jaswinder Dhoot (London, DE)
Date of First Priority Issue: Thursday February 2nd, 1995

Primate embryonic stem cells

Patent Number: 6200806

This is one of the patents that cover embryonic stem cells. These patents are under much controversy since they cover the composition of matter for all embryonic stem cells.

Inventor: Thomson, James A. (Madison, WI)
Assignee: Wisconsin Alumni Research Foundation (Madison, WI)
Date of First Priority Issue: Friday January 20th, 1995

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