Patents
Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
Patent Number: 7,311,905Stem cell populations are known from the cord blood as well as the placental matrix. In the current patent a stem cell population from the placenta is covered that possesses markers of adult stem cells as well as embryonic stem cells. For example, the first claim...
Inventors: Hariri; Robert J. (Florham Park, NJ)
Assignee: Anthrogenesis Corporation (Summit, NJ)
Date of First Priority Issue: Wednesday February 13th, 2002
2 Comments
2 Comments
Methods of controlling proliferation and differentiation of stem and progenitor cells
Patent Number: 7,312,078Homing of hematopoietic stem cells to their endosteal niche in the bone marrow is dependent in part on expression of the calcium sensing receptor. Since various chelating agents are known to modify calcium levels systemically, one interesting question is whether such chelating agents can be used to modulate stem cell expansion or differentiation ability. The...
Inventors: Peled; Tony (Mevaseret Zion, IL), Fibach; Eitan (Mevaseret Zion, IL), Treves; Avi (Mevaseret Zion, IL)
Assignee: Gamida Cell Ltd. (Savyon, IL); Hadasit Medical Research Services and Development, Ltd. (Jerusalem, IL)
Date of First Priority Issue: Tuesday February 17th, 1998
Method of treating mood disorders and/or anxiety disorders by brain stimulation
Patent Number: 7,313,442While studies have already demonstrated the ability of adult stem cells and embryonic stem cells to differentiate into neurons, the possibility of modulating new neurons to integrate into existing neurons, as well as enhance activity, is the philosophical "next...
Inventors: Velasco; Francisco (Mexico City, MX), Jimenez; Fiacro (Col. Roma, MX), Velasco; Marcos (Mexico City, MX), Lozano; Andres M. (Toronto, CA)
Assignee: Advanced Neuromodulation Systems, Inc. (Plano, TX)
Date of First Priority Issue: Friday April 30th, 2004
Methods for treating dental conditions using tissue scaffolds
Patent Number: 7,309,232This patent covers a method of forming new dentin (the calcified tissue of the body of the tooth, underneath the enamel) in teeth through administration of a tissue scaffold which stem cells can grow on and regenerate the dentin. Some of the stem cells covered include stem cells from the dental pulp. Indeed it is quite interesting...
Inventors: Rutherford; Bruce (Seattle, WA), Somogyi; Christopher (Woodinville, WA), White; Clinton (Raleigh, NC), Rabins; Erick (Seattle, WA)
Assignee: Dentigenix Inc. (Seattle, WA)
Date of First Priority Issue: Friday October 10th, 2003
Method for treatment of depression
Patent Number: 7,309,348The use of various types of energies to manipulate stem cells or to modulate the specific niche in which stem cells are placed is an exciting area of development. Photothera is a San Diego based company that has been clinically developing an area called "photoceuticals" for the past several years, primarily in relation to treatment...
Inventors: Streeter; Jackson (Reno, NV), De Taboada; Luis (Carlsbad, CA)
Assignee: Photothera, Inc. (Carlsbad, CA)
Date of First Priority Issue: Friday January 24th, 2003
Keratinocytes useful for the treatment of wounds
Patent Number: 7,306,943Although the patent describes a keratinocyte population, the fact that the cells claimed can proliferate past the Hayflick limit, stimulated us to discuss this patent. The use of allogeneic cells for covering burns and other types of wounds has been widely known in the art, however in the current patent a type of keratinocyte with immense proliferative potential is described. The patent...
Inventors: Eberhardt; Petra (Bad Schussenried, DE), Noe; Wolfgang (San Diego, CA), Reif; Katharina (Stadtbergen, DE)
Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG (Ingelheim, DE)
Date of First Priority Issue: Thursday October 10th, 2002
Methods and compositions for identifying morphogen analogs
Patent Number: 7,306,903One of the interesting methods of building up a patent portfolio is to cover not only therapeutic candidates, but also methods of identifying therapeutic candidates. In the current patent, the company Curis covers ways of identifying compounds that have morphogen activity. Specifically the patent covers methods of identifying compounds with similar biological effects as the morphogens OP-1...
Inventors: Sampath; Kuber T. (Holliston, MA), Harada; Shun-ichi (North Wales, PA), Rodan; Gideon A. (Bryn Mawr, PA)
Assignee: Curis, Inc. (Cambridge, MA)
Date of First Priority Issue: Wednesday July 26th, 1995
Oxpurine nucleosides and their congeners, and acyl, derivatives thereof, for improvement of hematopoiesis
Patent Number: 7,307,166This patent covers the composition of matter for several compounds and family of compounds that increase hematopoiesis. The compounds which are oxpurine nucleosides and their congeners, and acyl derivatives are demonstrated to accelerate hematopoietic reconstitution in both chemotherapy and irradiation induced suppression mouse models. In total the patent has over 70 examples. The compounds...
Inventors: von Borstel; Reid W. (Potomac, MD), Bamat; Michael K. (Potomac, MD), Hiltbrand; Bradley M. (Columbia, MD), Butler; James C. (Gaithersburg, MD), Shirali; Shyam (Gaithersburg, MD)
Assignee: Wellstat Therapeutics Corporation (Gaithersburg, MD)
Date of First Priority Issue: Wednesday October 28th, 1987
Herbal composition for treating CD33+ acute and chronic myeloid leukemia and a method thereof
Patent Number: 7,306,817Myeloid leukemias are known as conventional "stem cell malignancies" in that there is unequivocal evidence that the cell causing the propagation of the neoplasia is a transformed stem cell. This was what led to the discovery of tumor stem cells in solid tumors many years after. In the current patent a method of treating AML and CML...
Inventors: Bandyopadhyay; Santu (Calcutta, IN), Roy; Keshab Chandra (Calcutta, IN), Ray; Mitali (Calcutta, IN), Banerjee; Goutam (Calcutta, IN), Pal; Bikash Chandra (Calcutta, IN), Biswas; Tanusree (Calcutta, IN), Bhattacharya; Samir (Calcutta, IN)
Assignee: Council of Scientific and Industrial Research (New Delhi, IN)
Date of First Priority Issue: Tuesday January 30th, 2001
Cultures of GFAP nestin cells that differentiate to neurons
Patent Number: 7,303,912This patent covers, in its broadest issued claim, a type of stem cell that is useful for the generation of neurons. The cell population covered is a culture of cells expressing glial fibrillary acidic protein and nestin. In some dependent claims the cells may be extracted from the medial ganglionic eminence (MGE) and lateral ganglionic eminence (LGE). This patent is useful if the allogeneic...
Inventors: Wahlberg; Lars (Asnaes, DK), Campbell; Kenneth (Cincinnati, OH), Skogh; Charlotta (Malmo, SE), Eriksson; Cecilia (Falsterbo, SE), Wictorin; Klas (Lund, SE)
Assignee: NsGene A/S (Ballerup, DK)
Date of First Priority Issue: Monday October 25th, 1999