Category: Migration (25)
N-formyl peptides and Mesenchymal Stem Cells
New Orleans, Louisiana – One of the common themes in the study of stem cells is their ability to home into areas of damaged tissue. It is known that factors generated during hypoxia, such as stromal derived factor-1 generally attract stem cells, however other signals generated during injury that attract stem cells are less well understood. N-formyl peptides are cleavage products of...
Stem Cells Follow The Music
Frankfurt, Germany - One of the main issues with stem cell therapy is induction of their migration to area of need. In a report published recently (Aicher et al. Low-Energy Shock Wave for Enhancing Recruitment of Endothelial Progenitor Cells. A New Modality to Increase Efficacy of Cell Therapy in Chronic Hind Limb Ischemia. Circulation. 2006 Dec 4) a novel way of inducing migration...
Lipid Attraction of Stem Cells
Montreal, Canada -
Stromal Derived Factor (SDF)-1 is one of the cell-to-cell communication signals that is involved in stem cells (mesenchymal and hematopoietic) migration to sites of injury. In a recent paper, (Meriane et al. Cooperation of matrix metalloproteinases with the RhoA/Rho kinase and mitogen-activated protein kinase kinase-1/extracellular signal-regulated kinase signaling... Rehovot, Israel –
It is known that exosomes, small, viral-sized particles are used by the immune system to communicate with itself.
In a recent paper published by Lapidot’s group (Kalinkovich et al. Functional CXCR4-expressing microparticles and SDF-1 correlate with circulating acute myelogenous leukemia cells. Cancer Res. 2006 Nov... Singapore-
Scientists at Viacell announced the ability of unrestricted somatic stem cells (USSC) to enhance migration and repopulation of hematopoietic stem cells in an animal model through secretion of the stem cell chemotactic factor SDF-1.
Chan et al in a publication titled "ENHANCED IN VIVO HOMING OF UNCULTURED AND... 
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Exosomes and Stem Cells...
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Stem Cells Follow The Leader