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A New Age in Regenerative Medicine

Kyoto, Japan - In a recent paper Takahashi K et al. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors.Cell. 2007 Nov 20 generation of an "inducible pluripotent stem cell" or iPS from human skin was announced. Here is a video...
Sunday November 25th, 2007 @ 14:00:31 EST

Embryonic Stem Cells from Skin

[Watch the Video] This is a video describing the recent paper in Cell in which skin fibroblasts were retrodifferentiated to cells that "looked and felt" like embryonic stem cells. This is a major breakthrough in our knowledge of cell dedifferentiation and ability to use distinct, chemically-defined factors to coax an old cell into becoming a young cell again.
Sunday November 25th, 2007 @ 13:50:29 EST

Rapamycin turns stops Th17 but promotes Treg

Frederick, Maryland - Although mesenchymal stem cells are currently used in an allogeneic manner clinically, the question of whether they are truly tolerogenic is still debated. Other stem cell types such as CD34 or embryonic stem cells may possess different levels of...
Monday November 19th, 2007 @ 17:02:10 EST

Giving stem cells a kick in vitro with stromal derived factor-1

Cincinnati, OH - Commercialization of stem cell therapy is difficult since sometimes one doesn't really know what the product is. Additionally, there could be many products that are developed that are used in the implimentation of a single therapy. A current publication (Pasha et al. Preconditioning Enhances Cell Survival and Differentiation of Stem Cells during Transplantation in...
Monday November 19th, 2007 @ 15:30:37 EST

Medistem Publishes Menstrual Stem Cell Discovery

Medistem Announces Discovery of Novel Stem Cell Population in Menstrual Blood: Endometrial Regenerative Cells (ERC) Cells Produce 100,000 Times the Number of Growth Factors Found in Cord Blood SCOTTSDALE, AZ--(Marketwire - November 15, 2007) - Medistem Laboratories, Inc. (OTCBB: MDSM) (FRANKFURT: S2U) in collaboration with researchers from the University of Western Ontario, University of...
Sunday November 18th, 2007 @ 15:04:46 EST

Medistem (mdsm.ob) Discovers Menstrual Blood Stem Cells

[Watch the Video] This is one of many newsclips describing the discovery of pluripotent stem cells from the menstrual blood in a recent publication by the adult stem cell company Medistem (mdsm.ob).
Sunday November 18th, 2007 @ 12:19:20 EST

Allogeneic Serum is OK for Mesenchymal Stem Cell Culture

Stockholm, Sweden - The use of mesenchymal stem cells as a therapeutic is now a clinical reality. US companies such as Osiris Therapeutics are in Phase III of clinical trials, whereas clinics outside of the US such as Cellmedicine are offering such therapies as a fee for service. One of the problems with growing stem cells has always been the issue of fetal calf serum. Generally, cell...
Sunday November 11th, 2007 @ 16:14:31 EST

Latvian Stem Cell Meeting Success

The University of Latvia hosted an international conference entitled “Stem Cells and Cell Therapy” on November 2nd, 2007. StemCellPatents.com sent a representative to observe the meeting. Meeting organizer Dr Janis Ancans provided an overview of the state of the art in stem cell research, followed by data describing characterization of dermal, adipose, and bone marrow derived stem cell...
Sunday November 4th, 2007 @ 03:07:39 EST

Mesenchymal Stem Cells Talk with Hepatic Stellate Cells

Boston, MA - The ability of stem cells to inhibit progression of liver disease has been demonstrated in pilot human clinical trials. However the mechanisms by which bone marrow stem cell populations mediate antifibrotic effects are not completely known. In the mentioned clinical trial, administration of intravenous autologous bone...
Monday October 29th, 2007 @ 19:30:13 EST

TLR3 and 4 Ligation Abrogates Mesenchymal Stem Cell Immune Suppression

Florence, Italy - Mesenchymal stem cells are known to suppress immune responses in antigen specific and non-specific ways. In a recent paper (Liotta et al. TLR3 and TLR4 are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells And Can Inhibit Their T-cell...
Monday October 29th, 2007 @ 02:53:33 EST

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