News Posts
GM-CSF protecting diabetes
Sherbrooke, Quebec - The immune suppressive activity of mesenchymal and hematopoietic stem cells is well known. An interesting question however is whether activation/mobilization of these cells with pharmacological agents can be used to induce systemic immune modulation...Wednesday December 19th, 2007 @ 03:07:57 EST
Infectious Antigen Specific Tolerance by Dendritic Cells
Wuhan, China - The possibility of T regulatory cells inducing tolerance, both antigen specifically, and antigen-nonspecifically through the modulation of antigen presenting cell function has been previously established. What is more interesting is the concept of an antigen presenting cell being able to transfer tolerance without the...Wednesday December 19th, 2007 @ 02:54:16 EST
Molecular Mechanisms of Retina Regeneration in Chickens
Oxford, OH - Degeneration of the retina is a significant problem associated with several diseases that cause blindness, such as macular degeneration. In a recent paper (Haynes et al. BMP signaling mediates stem/progenitor cell-induced retina regeneration. Proc Natl Acad Sci U S A. 2007 Dec 14) the investigation of molecular signals associated wtih regeneration of the retina was...Tuesday December 18th, 2007 @ 11:37:32 EST
Tooth stem cells for heart attack
Valencia, Spain - Mesenchymal stem cells have been detected in bone marrow, peripheral blood, muscle and even in menstrual blood. Another...Monday December 17th, 2007 @ 04:20:06 EST
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Bone Marrow Mesenchymal Stem Cells Made to Produce Insulin
Taipei, Taiwan - In addition to their known ability to differentiate into muscle, bone, and neuronal cells, mesenchymal stem cells have been demonstrated to have the ability to differentiate into 2 Comments
Immune suppressant stimulating mesenchymal to bone differentiation
Shanghai, China - Mesenchymal stem cells are very useful since they can be administered across allogeneic barriers without need for immune suppression and can be differentiated into various tissues such as liver. In a current paper (Dai et al. Stimulation of osteogenic activity in mesenchymal stem cells by FK506. J Biomed Mater Res...Monday December 17th, 2007 @ 01:12:56 EST
Hepatocyte Growth Factor Helps After Heart Attack
Los Angeles, CA - It is known that mesenchymal stem cells are useful for treating patients after a heart attack. What is however unknown is exactly how these cells mediate their effects. On the one hand mesenchymal stem cells are known to inhibit various inflammatory...Tuesday December 11th, 2007 @ 18:08:51 EST
Extending Beta Cell Survival with Exendin-4
Toronto, Canada - Exendin-4 is an agonist of GLP-receptor 1, which is involved in not only increasing the mass of pancreatic beta cells, but has also been implicated in the stimulation of new neuron generation. In addition to exendin-4, agonists of the glucagon-like receptor include various incretin hormones. In a recent paper...Tuesday December 11th, 2007 @ 02:54:12 EST
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Mesenchymal stem cells inhibiting cancer
Chengdu, China - The use of mesenchymal stem cells is now a "clinical reality"https://www.stemcellpatents.com/news-show-154, primarily for the treatment of diseases such as multiple sclerosis and other inflammatory conditions. This is due to the known ability of mesenchymal stem cells to differentiate into various tissues, and also to...Monday December 10th, 2007 @ 03:20:53 EST
Generating lung epithelium from cord blood stem cells
Burlington, VT - Generation of lung epithelium de novo would be very useful in the treatment of chronic lung diseases. Unfortunately previous attempts to do this have not been extremely successful. In a recent study (Sueblinvong et al. Derivation of Lung Epithelium From Human Cord Blood-Derived Mesenchymal Stem Cells. Am J Respir Crit Care Med. 2007 Dec 6) human cord blood stem cells were...Monday December 10th, 2007 @ 02:59:41 EST
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